Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
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Myostatin from the heart: local and systemic actions in cardiac failure and muscle wastingNew Molecular Insights of Insulin in Diabetic CardiomyopathyHow exercise may amend metabolic disturbances in diabetic cardiomyopathyInsulin resistance as a physiological defense against metabolic stress: implications for the management of subsets of type 2 diabetesOptimization of cardiac metabolism in heart failureProtein quality control and metabolism: bidirectional control in the heartInsulin Signaling and Heart Failure.Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy.Insulin resistance and subclinical abnormalities of global and regional left ventricular function in patients with aortic valve sclerosis.High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance.Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts.Metabolomic analysis of pressure-overloaded and infarcted mouse hearts.Insulin inhibits cardiac contractility by inducing a Gi-biased β2-adrenergic signaling in hearts.Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance.Myocardial insulin resistance induced by high fat feeding in heart failure is associated with preserved contractile function.Lipid lowering and HDL raising gene transfer increase endothelial progenitor cells, enhance myocardial vascularity, and improve diastolic function.Nexilin, a cardiomyopathy-associated F-actin binding protein, binds and regulates IRS1 signaling in skeletal muscle cells.Selective homocysteine lowering gene transfer improves infarct healing, attenuates remodelling, and enhances diastolic function after myocardial infarction in miceThe endothelium-dependent effect of RTEF-1 in pressure overload cardiac hypertrophy: role of VEGF-BEnhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.Permanent ligation of the left anterior descending coronary artery in mice: a model of post-myocardial infarction remodelling and heart failureMaternal Hyperglycemia Directly and Rapidly Induces Cardiac Septal Overgrowth in Fetal Rats.Differential effects of Akt1 signaling on short- versus long-term consequences of myocardial infarction and reperfusion injuryLow-density lipoprotein receptor gene transfer in hypercholesterolemic mice improves cardiac function after myocardial infarction.Mechanisms of lipotoxicity in the cardiovascular system.Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic functionDiabetic cardiomyopathy and metabolic remodeling of the heart.Insulin resistance: metabolic mechanisms and consequences in the heart.Prenatal programming: adverse cardiac programming by gestational testosterone excess.Quantitative Non-canonical Amino Acid Tagging (QuaNCAT) Proteomics Identifies Distinct Patterns of Protein Synthesis Rapidly Induced by Hypertrophic Agents in Cardiomyocytes, Revealing New Aspects of Metabolic Remodeling.Insulin suppresses ischemic preconditioning-mediated cardioprotection through Akt-dependent mechanisms.Comparative mRNA and MicroRNA Profiling during Acute Myocardial Infarction Induced by Coronary Occlusion and Ablation Radio-Frequency Currents.Metformin in Diabetic Patients with Heart Failure: Safe and Effective?Biased G Protein-Coupled Receptor Signaling: New Player in Modulating Physiology and PathologyExercise mediated protection of diabetic heart through modulation of microRNA mediated molecular pathwaysMolecular mechanisms of diabetic cardiomyopathy.Interference with akt signaling protects against myocardial infarction and death by limiting the consequences of oxidative stress.Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy.Metformin therapy in diabetes: the role of cardioprotection.Insulin regulation of myocardial autophagy.
P2860
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P2860
Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Excessive cardiac insulin sign ...... pressure overload in rodents.
@en
type
label
Excessive cardiac insulin sign ...... pressure overload in rodents.
@en
prefLabel
Excessive cardiac insulin sign ...... pressure overload in rodents.
@en
P2093
P2860
P50
P356
P1476
Excessive cardiac insulin sign ...... pressure overload in rodents.
@en
P2093
Aika Nojima
E Dale Abel
Gou Young Koh
Haruhiro Toko
Hiroshi Akazawa
Hiroyuki Ikeda
Ichiro Shiojima
Ippei Shimizu
Junji Moriya
Kaoru Tateno
P2860
P304
P356
10.1172/JCI40096
P407
P577
2010-04-19T00:00:00Z