Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice. - Wikidata - wikimedia - TriplyDB

Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.

Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.

http://www.wikidata.org/entity/Q40256342

about

Meiotic transmission of an in vitro-assembled autonomous maize minichromosome A new generation of human artificial chromosomes for functional genomics and gene therapy A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges Novel method to load multiple genes onto a mammalian artificial chromosome HAC stability in murine cells is influenced by nuclear localization and chromatin organization.Bi-HAC vector system toward gene and cell therapy Human artificial chromosome with a conditional centromere for gene delivery and gene expression.Genetically modified pigs produced with a nonviral episomal vector.De novo assembly of potential linear artificial chromosome constructs capped with expansive telomeric repeats Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.Human artificial chromosomes for gene delivery and the development of animal models Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome.Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.Nucleic-acid based gene therapeutics: delivery challenges and modular design of nonviral gene carriers and expression cassettes to overcome intracellular barriers for sustained targeted expression.HACking the centromere chromatin code: insights from human artificial chromosomes.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications.Using human artificial chromosomes to study centromere assembly and function.Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster.Construction of rice mini-chromosomes by telomere-mediated chromosomal truncation.Manipulating transgenes using a chromosome vector A novel mouse model for Down syndrome that harbor a single copy of human artificial chromosome (HAC) carrying a limited number of genes from human chromosome 21.

P2860

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P2860

Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice.

http://www.wikidata.org/entity/Q40256342

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

@zh-hk

2006年論文

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2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

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2006年论文

@zh-cn

name

Human artificial chromosomes c ...... transmissible to progeny mice.

@en

type

label

Human artificial chromosomes c ...... transmissible to progeny mice.

@en

prefLabel

Human artificial chromosomes c ...... transmissible to progeny mice.

@en

P1433

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P2860

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P356

P1433

Journal of Biological Chemistry

P1476

Human artificial chromosomes c ...... transmissible to progeny mice.

@en

P2093

Kazuhiro Nishii

http://www.w3.org/2001/XMLSchema#string

Masashi Ikeno

http://www.w3.org/2001/XMLSchema#string

Nobutaka Suzuki

http://www.w3.org/2001/XMLSchema#string

Tuneko Okazaki

http://www.w3.org/2001/XMLSchema#string

P2860

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes.

Gene therapy: promises and problems.

Attenuated multi-mutated herpes simplex virus-1 for the treatment of malignant gliomas.

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe.

Advances in human artificial chromosome technology.

Efficient male and female germline transmission of a human chromosomal vector in mice.

Artificial and engineered chromosomes: developments and prospects for gene therapy.

Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis.

Chromosome manipulation: a systematic approach toward understanding human chromosome structure and function.

P304

26615-26623

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P31

scholarly article

P356

10.1074/JBC.M603053200

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P407

P433

36

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P478

281

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P577

2006-07-12T00:00:00Z

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P698

16837455

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