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The stoichiometry and biophysical properties of the Kv4 potassium channel complex with K+ channel-interacting protein (KChIP) subunits are variable, depending on the relative expression levelModulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)Structural basis for modulation of Kv4 K+ channels by auxiliary KChIP subunitsMultiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like propertiesThree-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamerStructural Insights into KChIP4a Modulation of Kv4.3 InactivationS-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivationKv4 potassium channel subunits control action potential repolarization and frequency-dependent broadening in rat hippocampal CA1 pyramidal neuronesInhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.Single particle image reconstruction of the human recombinant Kv2.1 channel.Mechanism of the modulation of Kv4:KChIP-1 channels by external K+A novel DPP6 isoform (DPP6-E) can account for differences between neuronal and reconstituted A-type K(+) channels.Mechanisms of Kv2.1 channel inhibition by celecoxib--modification of gating and channel blockExome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation.Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.Time- and voltage-dependent components of Kv4.3 inactivation.Modulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806.DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channelsK(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.Analysis of the contribution of I(to) to repolarization in canine ventricular myocardium.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.Gating charge immobilization in Kv4.2 channels: the basis of closed-state inactivation.A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism.Intra- and Intersubunit Dynamic Binding in Kv4.2 Channel Closed-State InactivationFunctional stoichiometry underlying KChIP regulation of Kv4.2 functional expressionDynamic coupling of voltage sensor and gate involved in closed-state inactivation of kv4.2 channelsThe neuronal Kv4 channel complex.Weighing the evidence for a ternary protein complex mediating A-type K+ currents in neurons.Closed-state inactivation in Kv4.3 isoforms is differentially modulated by protein kinase C.Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunitsMechanisms of closed-state inactivation in voltage-gated ion channels.Cytoplasmic domains and voltage-dependent potassium channel gating.Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder.Modulation of human Kv4.3/KChIP2 channel inactivation kinetics by cytoplasmic Ca²⁺.Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating.Ternary Kv4.2 channels recapitulate voltage-dependent inactivation kinetics of A-type K+ channels in cerebellar granule neurons.Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.Enhanced Sensitivity to Hyperpolarizing Inhibition in Mesoaccumbal Relative to Nigrostriatal Dopamine Neuron Subpopulations.Manipulating Kv4.2 identifies a specific component of hippocampal pyramidal neuron A-current that depends upon Kv4.2 expression.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
N-type inactivation features of Kv4.2 channel gating.
@en
type
label
N-type inactivation features of Kv4.2 channel gating.
@en
prefLabel
N-type inactivation features of Kv4.2 channel gating.
@en
P2093
P2860
P1433
P1476
N-type inactivation features of Kv4.2 channel gating.
@en
P2093
Andreas Nolting
Britta Callsen
Dirk Isbrandt
Kathrin Sauter
Manuel Gebauer
Olaf Pongs
Robert Bähring
P2860
P304
P356
10.1016/S0006-3495(04)74097-7
P407
P433
P577
2004-01-01T00:00:00Z