Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation. - Wikidata - wikimedia - TriplyDB

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation.

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation.

http://www.wikidata.org/entity/Q40271340

about

Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity.Functional regulation of phospholipase D expression in cancer and inflammation Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology Cell physiology of cAMP sensor Epac.Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac Real-time measurements of cAMP production in live Dictyostelium cells.Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.[EXPRESS] Epac and Nociceptor Sensitization.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up?Inflammatory signals enhance piezo2-mediated mechanosensitive currents.Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders.Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.A short splicing isoform of afadin suppresses the cortical axon branching in a dominant-negative manner.Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras Ras family small GTPase-mediated neuroprotective signaling in stroke.Epac activation sensitizes rat sensory neurons through activation of Ras.Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes.Phospholipase D signaling: orchestration by PIP2 and small GTPases.Ion channel regulation by Ras, Rho, and Rab small GTPases.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs.Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system.Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung.The role of Epac in the heart.Allosteric Modulation of GPCRs: New Insights and Potential Utility for Treatment of Schizophrenia and Other CNS Disorders.The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells.InlB-mediated Listeria monocytogenes internalization requires a balanced phospholipase D activity maintained through phospho-cofilin.Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway.Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation.

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P2860

Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation.

http://www.wikidata.org/entity/Q40271340

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

@zh-tw

2006年论文

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2006年论文

@zh

2006年论文

@zh-cn

name

Cyclic AMP-dependent and Epac- ...... o phospholipase D stimulation.

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type

label

Cyclic AMP-dependent and Epac- ...... o phospholipase D stimulation.

@en

prefLabel

Cyclic AMP-dependent and Epac- ...... o phospholipase D stimulation.

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P1433

Journal of Biological Chemistry

P1476

Cyclic AMP-dependent and Epac- ...... o phospholipase D stimulation.

@en

P2093

Christian Rimmbach

http://www.w3.org/2001/XMLSchema#string

Christof Börgermann

http://www.w3.org/2001/XMLSchema#string

Dieter Rosskopf

http://www.w3.org/2001/XMLSchema#string

Karl H Jakobs

http://www.w3.org/2001/XMLSchema#string

Maider López De Jesús

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Martina Schmidt

http://www.w3.org/2001/XMLSchema#string

Matthias B Stope

http://www.w3.org/2001/XMLSchema#string

Paschal A Oude Weernink

http://www.w3.org/2001/XMLSchema#string

Viktoria N Ananaba

http://www.w3.org/2001/XMLSchema#string

Yvonne Mahlke

http://www.w3.org/2001/XMLSchema#string

P2860

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A family of cAMP-binding proteins that directly activate Rap1

Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap

An Eph receptor regulates integrin activity through R-Ras

The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase D

P304

21837-21847

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P31

scholarly article

P356

10.1074/JBC.M604156200

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P407

P433

31

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P478

281

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P50

Martin C. Michel

P577

2006-06-05T00:00:00Z

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P5875

7027698

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16754664

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P921

G protein-coupled receptor