Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
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Thermal unfolding pathway of PHD2 catalytic domain in three different PHD2 species: computational approachesProlyl hydroxylase domain 2 protein is a strong prognostic marker in human gastric cancerCellular characterization of ultrasound-stimulated microbubble radiation enhancement in a prostate cancer xenograft model.Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation.Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2.Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts.Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment.Overexpression of the HIF hydroxylases PHD1, PHD2, PHD3 and FIH are individually and collectively unfavorable prognosticators for NSCLC survivalProlyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells.Immunohistochemical analysis of the mechanistic target of rapamycin and hypoxia signalling pathways in basal cell carcinoma and trichoepithelioma.Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.Expression and DNA methylation levels of prolyl hydroxylases PHD1, PHD2, PHD3 and asparaginyl hydroxylase FIH in colorectal cancer.Role of compartmentalization on HiF-1α degradation dynamics during changing oxygen conditions: a computational approach.Double immunohistochemical staining method for HIF-1alpha and its regulators PHD2 and PHD3 in formalin-fixed paraffin-embedded tissues.Analysis of HIF-1a and its regulator, PHD2, in retroperitoneal sarcomas: clinico-pathologic implications.Tumor PHD2 expression is correlated with clinical features and prognosis of patients with HCC receiving liver resectionThe role of HIF prolyl hydroxylases in tumour growth.Prolyl hydroxylase domain protein 3 and asparaginyl hydroxylase factor inhibiting HIF-1 levels are predictive of tumoral behavior and prognosis in hepatocellular carcinoma.Nuclear-cytoplasmatic shuttling of proteins in control of cellular oxygen sensing.HIF-1 in cancer therapy: two decade long story of a transcription factor.Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide.A Genetically Encoded FRET Sensor for Hypoxia and Prolyl Hydroxylases.Hypoxia-inducible factor prolyl hydroxylase 2 (PHD2) is a direct regulator of epidermal growth factor receptor (EGFR) signaling in breast cancer.A hidden aggregation-prone structure in the heart of hypoxia inducible factor prolyl hydroxylase.Knockdown of prolyl-4-hydroxylase domain 2 inhibits tumor growth of human breast cancer MDA-MB-231 cells by affecting TGF-β1 processing.Expression of hypoxia-inducible factor-1α, vascular endothelial growth factor and prolyl hydroxylase domain protein 2 in cutaneous squamous cell carcinoma and precursor lesions and their relationship with histological stages and clinical features.
P2860
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P2860
Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Overexpression and nuclear tra ...... ted with tumor aggressiveness.
@en
type
label
Overexpression and nuclear tra ...... ted with tumor aggressiveness.
@en
prefLabel
Overexpression and nuclear tra ...... ted with tumor aggressiveness.
@en
P2093
P1476
Overexpression and nuclear tra ...... ated with tumor aggressiveness
@en
P2093
Krista Rantanen
Marjaana Luukkaa
Pauliina Kronqvist
Pekka Heikkinen
Reidar Grenman
Terhi Jokilehto
P304
P356
10.1158/1078-0432.CCR-05-2022
P407
P577
2006-02-01T00:00:00Z