Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
about
Family-specific degenerate primer design: a tool to design consensus degenerated oligonucleotidesRIG-I enhanced interferon independent apoptosis upon Junin virus infection.Toll-like receptor 2-mediated innate immune responses against Junín virus in mice lead to antiviral adaptive immune responses during systemic infection and do not affect viral replication in the brainRescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.Junin virus infects mouse cells and induces innate immune responses.Watching every step of the way: junín virus attenuation markers in the vaccine lineage.The major determinant of attenuation in mice of the Candid1 vaccine for Argentine hemorrhagic fever is located in the G2 glycoprotein transmembrane domain.Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GPEpistastic interactions within the Junín virus envelope glycoprotein complex provide an evolutionary barrier to reversion in the live-attenuated Candid#1 vaccine.Complete Genome Sequence of a Mammarenavirus Harbored by Rodents on Hainan Island, China.
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P2860
Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
@en
type
label
Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
@en
prefLabel
Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
@en
P2093
P50
P1433
P1476
Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy
@en
P2093
Javier Alonso Iserte
Mario Enrique Lozano
Sandra Elizabeth Goñi
P2860
P2888
P304
P356
10.1007/S11262-010-0450-2
P577
2010-02-11T00:00:00Z
P5875
P6179
1049868630