In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability.
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Emergence of micronuclei as a genomic biomarkerEmerging metrology for high-throughput nanomaterial genotoxicologyComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterHerpes simplex virus type 1 penetrates the basement membrane in human nasal respiratory mucosaApplication of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.Optimized automated data analysis for the cytokinesis-block micronucleus assay using imaging flow cytometry for high throughput radiation biodosimetry.High content flow cytometric micronucleus scoring method is applicable to attachment cell linesLaser scanning cytometry for automation of the micronucleus assayEvaluation of the automated MicroFlow® and Metafer™ platforms for high-throughput micronucleus scoring and dose response analysis in human lymphoblastoid TK6 cells.Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships.Automated analysis of the cytokinesis-block micronucleus assay for radiation biodosimetry using imaging flow cytometry.In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicityThe Application of Imaging Flow Cytometry to High-Throughput Biodosimetry.Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assayNew and emerging technologies for genetic toxicity testing.How accurate is in vitro prediction of carcinogenicity?The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance.Cancer cell micronucleus: an update on clinical and diagnostic applications.Flow cytometry vs optical microscopy in the evaluation of the genotoxic potential of xenobiotic compounds.Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay.Recommendations, evaluation and validation of a semi-automated, fluorescent-based scoring protocol for micronucleus testing in human cells.Co-assessment of cell cycle and micronucleus frequencies demonstrates the influence of serum on the in vitro genotoxic response to amorphous monodisperse silica nanoparticles of varying sizes.Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: protocol optimization and transferability assessment.Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and γH2AX analysis.In vitro micronucleus screening of pharmaceutical candidates by flow cytometry in Chinese hamster V79 cells.A flow cytometry based in vitro micronucleus assay in TK6 cells--validation using early stage pharmaceutical development compounds.Genetic and rat toxicity studies of cyclodextrin glucanotransferase.In vivo genotoxicity assessment in rats exposed to Prestige-like oil by inhalation.Miniaturized flow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action.Interpreting in vitro micronucleus positive results: simple biomarker matrix discriminates clastogens, aneugens, and misleading positive agents.Investigating the Generalizability of the MultiFlow® DNA Damage Assay and Several Companion Machine Learning Models with a Set of 103 Diverse Test Chemicals.Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1.Multi-parameter dose estimations in radiation biodosimetry using the automated cytokinesis-block micronucleus assay with imaging flow cytometry.Further evaluation of a flow cytometric in vitro micronucleus assay in CHO-K1 cells: a reliable platform that detects micronuclei and discriminates apoptotic bodies.Miniaturized flow cytometry-based in vitro primary human lymphocyte micronucleus assay-validation study.toxicity evaluation of silica-coated iron oxide nanoparticles in human SHSY5Y neuronal cellsAutomation of the in vitro micronucleus assay using the Imagestream imaging flow cytometer
P2860
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P2860
In vitro micronucleus scoring by flow cytometry: differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
In vitro micronucleus scoring ...... in enhances assay reliability.
@en
type
label
In vitro micronucleus scoring ...... in enhances assay reliability.
@en
prefLabel
In vitro micronucleus scoring ...... in enhances assay reliability.
@en
P2093
P2860
P356
P1476
In vitro micronucleus scoring ...... in enhances assay reliability.
@en
P2093
Siân E Cairns
Stephen D Dertinger
Steven M Bryce
Svetlana L Avlasevich
P2860
P356
10.1002/EM.20170
P577
2006-01-01T00:00:00Z