Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease.
about
beta-Amyloid degradation and Alzheimer's diseaseSEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide productionProgressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteinsCerebral amyloid angiopathy: amyloid beta accumulates in putative interstitial fluid drainage pathways in Alzheimer's diseasePro-domain removal in ASP-2 and the cleavage of the amyloid precursor are influenced by pHNew insights into coupling and uncoupling of cerebral blood flow and metabolism in the brainPathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseNeuropathological alterations in Alzheimer diseaseZyme, a novel and potentially amyloidogenic enzyme cDNA isolated from Alzheimer's disease brainPurification and Characterization of Recombinant N-Terminally Pyroglutamate-Modified Amyloid-β Variants and Structural Analysis by Solution NMR SpectroscopyIdentification of a Novel Parallel β-Strand Conformation within Molecular Monolayer of Amyloid PeptideComparison of the structures of beta amyloid peptide (25-35) and substance P in trifluoroethanol/water solution.Sequencing of peptides phosphorylated on serines and threonines by post-source decay in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.Mechanism of accelerated assembly of beta-amyloid filaments into fibrils by KLVFFK(6).Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease.Immunological memory to hyperphosphorylated tau in asymptomatic individuals.Amyloid-beta associated with chitosan nano-carrier has favorable immunogenicity and permeates the BBB.Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide.Microglia and the immune pathology of Alzheimer disease.A novel signaling molecule for neuropeptide action: activity-dependent neuroprotective protein.NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation.A liposome-based therapeutic vaccine against beta -amyloid plaques on the pancreas of transgenic NORBA mice.Amyloid-beta aggregation: selective inhibition of aggregation in mixtures of amyloid with different chain lengths.Mixed oligomers and monomeric amyloid-β disrupts endothelial cells integrity and reduces monomeric amyloid-β transport across hCMEC/D3 cell line as an in vitro blood-brain barrier model.Amyloid structure: conformational diversity and consequences.Surface behavior and lipid interaction of Alzheimer beta-amyloid peptide 1-42: a membrane-disrupting peptideInvolvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing and β-amyloid deposition in Alzheimer's disease models.Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain.Alzheimer and beta-amyloid-treated fibroblasts demonstrate a decrease in a memory-associated GTP-binding protein, Cp20Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD.Intracranial injection of AAV expressing NEP but not IDE reduces amyloid pathology in APP+PS1 transgenic mice.hnRNP C increases amyloid precursor protein (APP) production by stabilizing APP mRNAApolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease.Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation.Amyloid beta inhibits olfactory bulb activity and the ability to smellDetection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibodyAmyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold.Do statins slow down Alzheimer's disease? A review.Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy.Doubly Phosphorylated Peptide Vaccines to Protect Transgenic P301S Mice against Alzheimer's Disease Like Tau Aggregation.
P2860
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P2860
Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Physiological production of th ...... hanism of Alzheimer's disease.
@en
type
label
Physiological production of th ...... hanism of Alzheimer's disease.
@en
prefLabel
Physiological production of th ...... hanism of Alzheimer's disease.
@en
P1476
Physiological production of th ...... hanism of Alzheimer's disease.
@en
P2093
P304
P356
10.1016/0166-2236(93)90008-A
P577
1993-10-01T00:00:00Z