The MUC1 SEA module is a self-cleaving domain. - Wikidata - wikimedia - TriplyDB

The MUC1 SEA module is a self-cleaving domain.

The MUC1 SEA module is a self-cleaving domain.

http://www.wikidata.org/entity/Q40403573

about

A minimal fragment of MUC1 mediates growth of cancer cells MUC1* mediates the growth of human pluripotent stem cells PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity Non-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasion A cleavage-potentiated fragment of tear lacritin is bactericidal.Mucins in cancer: function, prognosis and therapy Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling)An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma Solution structure of a truncated anti-MUC1 DNA aptamer determined by mesoscale modeling and NMR Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing Characterization of a gene family encoding SEA (sea-urchin sperm protein, enterokinase and agrin)-domain proteins with lectin-like and heme-binding properties from Schistosoma japonicum Cleavage of influenza virus hemagglutinin by airway proteases TMPRSS2 and HAT differs in subcellular localization and susceptibility to protease inhibitors N-Glycosylation of the MUC1 mucin in epithelial cells and secretions.MUC1 mucin interacts with calcium-modulating cyclophilin ligand.Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer.Soluble perlecan domain I enhances vascular endothelial growth factor-165 activity and receptor phosphorylation in human bone marrow endothelial cells.MUC1: a multifaceted oncoprotein with a key role in cancer progression.Membrane-tethered mucins have multiple functions on the ocular surface.EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1.The gastrointestinal mucus system in health and disease The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop Protein multifunctionality: principles and mechanisms.Functional targeting of the MUC1 oncogene in human cancers MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signaling Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- mice.MUC1 expression and anti-MUC1 serum immune response in head and neck squamous cell carcinoma (HNSCC): a multivariate analysis.Role of the unfolded protein response in regulating the mucin-dependent filamentous-growth mitogen-activated protein kinase pathway.Post-translational regulation of signaling mucins.A valid mouse model of AGRIN-associated congenital myasthenic syndrome.The structure of the PanD/PanZ protein complex reveals negative feedback regulation of pantothenate biosynthesis by coenzyme A.MUC1 is a substrate for gamma-secretase The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.Muc1 enhances the β-catenin protective pathway during ischemia-reperfusion injury MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches.MUC1 oncoprotein blocks death receptor-mediated apoptosis by inhibiting recruitment of caspase-8.Genetic regulation of MUC1 alternative splicing in human tissues Epidemic Keratoconjunctivitis-Causing Adenoviruses Induce MUC16 Ectodomain Release To Infect Ocular Surface Epithelial Cells.Release of membrane-associated mucins from ocular surface epithelia.Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer.Amplification of MUC1 in prostate cancer metastasis and CRPC development

P2860

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P2860

The MUC1 SEA module is a self-cleaving domain.

http://www.wikidata.org/entity/Q40403573

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

The MUC1 SEA module is a self-cleaving domain.

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The MUC1 SEA module is a self-cleaving domain.

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P1433

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P1476

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P2093

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P2860

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P1433

Journal of Biological Chemistry

P1476

The MUC1 SEA module is a self-cleaving domain

@en

P2093

Chava Gil-Henn

http://www.w3.org/2001/XMLSchema#string

Daniel B Rubinstein

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Fiana Levitin

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Mordechai Weiss

http://www.w3.org/2001/XMLSchema#string

Nechama I Smorodinsky

http://www.w3.org/2001/XMLSchema#string

Omer Stern

http://www.w3.org/2001/XMLSchema#string

Ravit Ziv

http://www.w3.org/2001/XMLSchema#string

Zofnat Prokocimer

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P2860

Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin

InBase: the Intein Database

Structural insights into the mechanism of intramolecular proteolysis

Three-dimensional structure of Escherichia coli asparagine synthetase B: a short journey from substrate to product

Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)

Penicillin acylase has a single-amino-acid catalytic centre

P304

33374-33386

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P31

scholarly article

P356

10.1074/JBC.M506047200

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P407

P433

39

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P478

280

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P50

Daniel H Wreschner

P577

2005-06-29T00:00:00Z

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P5875

7755701

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P698

15987679

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