GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
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Phosphoproteomic Analysis of the Mouse Brain Cytosol Reveals a Predominance of Protein Phosphorylation in Regions of Intrinsic Sequence DisorderG protein-coupled receptor kinase 2 positively regulates epithelial cell migrationGIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnoverThe multifunctional GIT family of proteinsBiochemical and functional characterization of the interaction between liprin-α1 and GIT1: implications for the regulation of cell motilityGIT1 is a novel MEK1-ERK1/2 scaffold that localizes to focal adhesionsExtracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.Paxillin-kinase-linker tyrosine phosphorylation regulates directional cell migration.MEK1 activation by PAK: a novel mechanism.The cell adhesion-associated protein Git2 regulates morphogenetic movements during zebrafish embryonic development.Cadherins and Pak1 control contact inhibition of proliferation by Pak1-betaPIX-GIT complex-dependent regulation of cell-matrix signaling.Placental growth factor (PlGF) enhances breast cancer cell motility by mobilising ERK1/2 phosphorylation and cytoskeletal rearrangement.GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone massMicroRNA-149 targets GIT1 to suppress integrin signaling and breast cancer metastasisPhosphorylation of G protein-coupled receptor kinase 2-interacting protein 1 tyrosine 392 is required for phospholipase C-gamma activation and podosome formation in vascular smooth muscle cells.Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.Specific dephosphorylation at tyr-554 of git1 by ptprz promotes its association with paxillin and hic-5.Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translationThe cytoskeletal regulatory scaffold protein GIT2 modulates mesenchymal stem cell differentiation and osteoblastogenesis.Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity.The PAK system links Rho GTPase signaling to thrombin-mediated platelet activationRoles of P21-activated kinases and associated proteins in epithelial wound healing.GIT1 mediates VEGF-induced podosome formation in endothelial cells: critical role for PLCgammaThe adaptor protein and Arf GTPase-activating protein Cat-1/Git-1 is required for cellular transformation.Oxytocin induces the migration of prostate cancer cells: involvement of the Gi-coupled signaling pathway.New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration.GIT1 mediates HDAC5 activation by angiotensin II in vascular smooth muscle cellsIdentification of an intramolecular interaction important for the regulation of GIT1 functions.Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.G-protein-coupled receptor kinase interacting protein-1 mediates intima formation by regulating vascular smooth muscle proliferation, apoptosis, and migrationERK Signals: Scaffolding Scaffolds?G-protein-coupled receptor kinase interacting protein-1 is required for pulmonary vascular developmentRhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.Periodic mechanical stress activates MEK1/2-ERK1/2 mitogenic signals in rat chondrocytes through Src and PLCγ1.
P2860
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P2860
GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
@en
type
label
GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
@en
prefLabel
GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
@en
P2093
P2860
P356
P1476
GIT1 is a scaffold for ERK1/2 activation in focal adhesions.
@en
P2093
Guoyong Yin
Qinlei Zheng
P2860
P304
27705-27712
P356
10.1074/JBC.M502271200
P407
P577
2005-05-27T00:00:00Z