Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2.
about
The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factorPhosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcriptionActivation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBFThe species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factorCasein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcriptionA functional screen in human cells identifies UBF2 as an RNA polymerase II transcription factor that enhances the beta-catenin signaling pathwayDNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription.Ribin, a protein encoded by a message complementary to rRNA, modulates ribosomal transcription and cell proliferationUBF levels determine the number of active ribosomal RNA genes in mammalsRecruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylationPhosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein.Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor.Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkitThe nucleolus: a paradigm for cell proliferation and aging.Survey and summary: transcription by RNA polymerases I and III.A specialized form of RNA polymerase I, essential for initiation and growth-dependent regulation of rRNA synthesis, is disrupted during transcriptionDifferential roles of phosphorylation in the formation of transcriptional active RNA polymerase I.Histone acetyltransferase and protein kinase activities copurify with a putative Xenopus RNA polymerase I holoenzyme self-sufficient for promoter-dependent transcriptionA kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription.Structure of recombinant rat UBF by electron image analysis and homology modellingUBF activates RNA polymerase I transcription by stimulating promoter escape.CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interactionTranscription and tyranny in the nucleolus: the organization, activation, dominance and repression of ribosomal RNA genesCoordinated decreases in rRNA gene transcription factors and rRNA synthesis during muscle cell differentiation.xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity.The RNA polymerase I transactivator upstream binding factor requires its dimerization domain and high-mobility-group (HMG) box 1 to bend, wrap, and positively supercoil enhancer DNA.Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I.Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1.Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophyThe RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acidsThe HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase IMouse rRNA gene transcription factor mUBF requires both HMG-box1 and an acidic tail for nucleolar accumulation: molecular analysis of the nucleolar targeting mechanism.DNA looping in the RNA polymerase I enhancesome is the result of non-cooperative in-phase bending by two UBF molecules.HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF.The nucleolar transcription activator UBF relieves Ku antigen-mediated repression of mouse ribosomal gene transcription.RNA polymerase I catalysed transcription of insert viral cDNARrn3 becomes inactivated in the process of ribosomal DNA transcription.Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.Functional differences between the two splice variants of the nucleolar transcription factor UBF: the second HMG box determines specificity of DNA binding and transcriptional activity.
P2860
Q24299223-299D4A62-C908-47CD-935D-C79A950E0605Q24555090-C72EDA90-F30C-48CA-8A41-FEBAC02A61E4Q24626533-302DA177-CA44-48A9-8E48-2EFA1DB32E74Q24650868-8B89FEE3-E163-428A-A421-B326E85D1D63Q24670888-CD0A2B33-D60C-4ED0-905F-57418F07776EQ24673336-AA246979-1BFF-49DF-8E2D-4E36FD5DCC91Q27934982-3F0CD3D0-3BA8-41E5-BFBE-788190A2904AQ28578720-380667F1-D830-49A2-A2A7-51B82DF5EF38Q28585859-5D078923-82EB-4B20-881A-E80FC8B131B5Q28611495-D26C7321-2CE8-470B-9CE0-2DC5ABABBC3CQ30454337-4C5731BF-39DF-4584-A7B4-23326E1658E7Q30464081-0B06EE06-DFA5-4E30-86BE-3E217B48FFEBQ30906623-5D710BA5-5A87-42DF-AE1E-7B0FE780051EQ33786951-05902DAE-002D-481D-BBCA-526D95AB73B4Q33787605-09D6E12A-DD75-48E3-9C86-1CAE95058A73Q33889052-6ADA15C7-73C3-4A11-99E7-F2996DA0F977Q33951831-AAD48887-B01F-43E9-B5F5-8A3C5988E4D8Q33957262-C9A319F3-07F7-44BB-AF3E-DA452F0C5334Q33957731-01D67633-4375-4888-8271-29224C94E849Q33967873-C71E0AE8-9EDA-41C1-8AB1-EB2C1F9106F1Q34594678-AEA7BDE4-B35F-4ACF-BBBB-C425C5C224FEQ34870935-75E20AF8-D000-4D80-B83D-CEDFA308FA6DQ35127996-C93D1546-7857-4DC0-A95A-6D74174B268FQ35625586-38338DD6-AE44-4A49-99CD-B82EA7F2A106Q36500181-B3A808CB-C20B-4EFE-BA80-D8E98EE0434AQ36651505-1D550312-22D7-4E87-8D90-95D1B3C522B6Q36666683-2A961287-5F63-4C8A-890E-6D77F942B398Q36853026-14D760F9-CB8C-4B9D-8842-FF312CEE75A3Q37197152-6441D435-F97A-4798-B537-22901217B259Q37417774-D8C1AE04-DB2A-411B-87A5-340CF26098FCQ38306334-49BD8DAB-19E8-4E5B-BACD-9D74C7BE3649Q38312336-B1A0977D-72BB-454E-B1CC-A112466FF489Q38325623-D065D10E-D632-44EB-95EC-B69BEFF00896Q39096651-1F6807E6-0075-443B-8ECF-DFA04567ED2BQ40396712-5B1A8337-4AC7-4E15-9014-19AF8A2EDF59Q40406792-821902DF-413D-4382-8CF1-CB365EF45B03Q40408805-A1BA23BA-7A24-4520-964B-C19086C54E07Q40662645-F6AD4272-1552-4190-B654-46C19EE11D31Q40731596-4C4354C6-D77D-4CA4-A4D9-BB9A9ABB3E51Q40790630-0870AE6E-A806-46BD-AD5E-4CB5EDB75997
P2860
Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Analysis of the phosphorylatio ...... ription factors UBF1 and UBF2.
@en
type
label
Analysis of the phosphorylatio ...... ription factors UBF1 and UBF2.
@en
prefLabel
Analysis of the phosphorylatio ...... ription factors UBF1 and UBF2.
@en
P2093
P2860
P356
P1476
Analysis of the phosphorylatio ...... ription factors UBF1 and UBF2.
@en
P2093
P2860
P304
P356
10.1093/NAR/20.6.1301
P577
1992-03-01T00:00:00Z