Suppression of hREV1 expression reduces the rate at which human ovarian carcinoma cells acquire resistance to cisplatin.
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Suppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapyEukaryotic translesion polymerases and their roles and regulation in DNA damage toleranceUnconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y Family DNA Polymerases ι and Rev1Multifaceted Recognition of Vertebrate Rev1 by Translesion Polymerases ζ and κREV3L confers chemoresistance to cisplatin in human gliomas: the potential of its RNAi for synergistic therapyDifferential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links.Error-prone translesion synthesis mediates acquired chemoresistanceDNA polymerase zeta (pol zeta) in higher eukaryotes.REV3L, a promising target in regulating the chemosensitivity of cervical cancer cells.DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.DNA polymerase ζ is a major determinant of resistance to platinum-based chemotherapeutic agents.Mechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.Translesion DNA synthesis and mutagenesis in eukaryotesIdentification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.Overexpression of Rev1 promotes the development of carcinogen-induced intestinal adenomas via accumulation of point mutation and suppression of apoptosis proportionally to the Rev1 expression level.Minor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis.Knockdown of REV3 synergizes with ATR inhibition to promote apoptosis induced by cisplatin in lung cancer cells.
P2860
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P2860
Suppression of hREV1 expression reduces the rate at which human ovarian carcinoma cells acquire resistance to cisplatin.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Suppression of hREV1 expressio ...... quire resistance to cisplatin.
@en
type
label
Suppression of hREV1 expressio ...... quire resistance to cisplatin.
@en
prefLabel
Suppression of hREV1 expressio ...... quire resistance to cisplatin.
@en
P2093
P356
P1476
Suppression of hREV1 expressio ...... quire resistance to cisplatin.
@en
P2093
Julie Trang
Stephen B Howell
Tsuyoshi Okuda
Xinjian Lin
P304
P356
10.1124/MOL.104.010579
P577
2005-03-09T00:00:00Z