p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.
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The exosome complex establishes a barricade to erythroid maturationEffects of overexpression of HBP1 upon growth and differentiation of leukemic myeloid cellsCyclic AMP signaling inhibits megakaryocytic differentiation by targeting transcription factor 3 (E2A) cyclin-dependent kinase inhibitor 1A (CDKN1A) transcriptional axis.Roles for p21waf1/cip1 and p27kip1 during the adaptation response to massive intestinal resection.Forced expression of cyclin-dependent kinase 6 confers resistance of pro-B acute lymphocytic leukemia to Gleevec treatmentBrachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathwayHigh p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cyclep21 as a transcriptional co-repressor of S-phase and mitotic control genesSKP2 oncogene is a direct MYC target gene and MYC down-regulates p27(KIP1) through SKP2 in human leukemia cells.Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma CellsCytokines in the differentiation therapy of leukemia: from laboratory investigations to clinical applications.The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint.Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21Focused screening of mitochondrial metabolism reveals a crucial role for a tumor suppressor Hbp1 in ovarian reserve.alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.p27kip1 maintains a subset of leukemia stem cells in the quiescent state in murine MLL-leukemia.Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation.Overexpression of PHRF1 attenuates the proliferation and tumorigenicity of non-small cell lung cancer cells.Elevated expression of STIM1 is involved in lung tumorigenesis.CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells.SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status.Defective erythropoiesis in a mouse model of reduced Fbxo7 expression due to decreased p27 expression.MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27(KIP1.).The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma.Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells.PLSCR1/IP3R1/Ca2+ axis contributes to differentiation of primary AML cells induced by wogonoside.EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation.Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest.p27 in FLT3-driven acute myeloid leukemia: many roads lead to ruin.p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes.SKP2 siRNA inhibits the degradation of P27kip1 and down-regulates the expression of MRP in HL-60/A cells.MYC accelerates p21CIP-induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells.Chalepin: A Compound from Ruta angustifolia L. Pers Exhibits Cell Cycle Arrest at S phase, Suppresses Nuclear Factor-Kappa B (NF-κB) Pathway, Signal Transducer and Activation of Transcription 3 (STAT3) Phosphorylation and Extrinsic Apoptotic PathwayThe nuclear mitotic apparatus protein NuMA controls rDNA transcription and mediates the nucleolar stress response in a p53-independent manner.ABT-263 induces G1/G0-phase arrest, apoptosis and autophagy in human esophageal cancer cells in vitro.Proteomic analysis of cell cycle arrest and differentiation induction caused by ATPR, a derivative of all-trans retinoic acid, in human gastric cancer SGC-7901 cells.Gambogic acid induces growth inhibition and differentiation via upregulation of p21waf1/cip1 expression in acute myeloid leukemia cells.
P2860
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P2860
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
p21Cip1 and p27Kip1 induce dis ...... ams in myeloid leukemia cells.
@en
type
label
p21Cip1 and p27Kip1 induce dis ...... ams in myeloid leukemia cells.
@en
prefLabel
p21Cip1 and p27Kip1 induce dis ...... ams in myeloid leukemia cells.
@en
P2093
P2860
P356
P1476
p21Cip1 and p27Kip1 induce dis ...... ams in myeloid leukemia cells.
@en
P2093
Carlos Richard
John Sedivy
M Dolores Delgado
María J Muñoz-Alonso
P2860
P304
18120-18129
P356
10.1074/JBC.M500758200
P407
P577
2005-03-03T00:00:00Z