Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.
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High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expressionCarboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosisIntimal redox stress: accelerated atherosclerosis in metabolic syndrome and type 2 diabetes mellitus. Atheroscleropathy.Prevalence, predisposition and prevention of type II diabetes.Lipid-Induced Insulin Resistance in Skeletal Muscle: The Chase for the Culprit Goes from Total Intramuscular Fat to Lipid Intermediates, and Finally to Species of Lipid IntermediatesAn Update on the Effect of Incretin-Based Therapies on β-Cell Function and MassDiabetes mellitus related bone metabolism and periodontal diseaseFatty acids, obesity, and insulin resistance: time for a reevaluationType 2 diabetes in East Asians: similarities and differences with populations in Europe and the United StatesEndoplasmic reticulum stress in the β-cell pathogenesis of type 2 diabetesType 2 diabetes: etiology and reversibilityMGL2/YMR210w encodes a monoacylglycerol lipase in Saccharomyces cerevisiae.UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagyA novel glucokinase regulator in pancreatic beta cells: precursor of propionyl-CoA carboxylase beta subunit interacts with glucokinase and augments its activityIdentifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetesLeptin, troglitazone, and the expression of sterol regulatory element binding proteins in liver and pancreatic isletsLipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipidsA combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki ratsMCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gammaMeta-modeling of methylprednisolone effects on glucose regulation in ratsIdentification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogueThe CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic isletsAdenovirus-mediated overexpression of liver carnitine palmitoyltransferase I in INS1E cells: effects on cell metabolism and insulin secretionRegulation of the insulin gene by glucose and fatty acidsResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Cholesterol accumulation increases insulin granule size and impairs membrane trafficking.UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells.Atmospheric pressure covalent adduct chemical ionization tandem mass spectrometry for double bond localization in monoene- and diene-containing triacylglycerols.Reduction of islet pyruvate carboxylase activity might be related to the development of type 2 diabetes mellitus in Agouti-K miceGlucolipotoxicity of the pancreatic beta cell.New-onset diabetes mellitus associated with protease inhibitor therapy in an HIV-positive patient: case report and review.Fatty diabetic lung: altered alveolar structure and surfactant protein expressionNovel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosisPotential interactions of zinc in the neuroendocrine-endocrine disturbances of diabetes mellitus type 2.Pathogenesis of insulin resistance in skeletal muscle.Effect of renal lipid accumulation on proximal tubule Na+/H+ exchange and ammonium secretion.Lipid infusion lowers sympathetic nervous activity and leads to increased beta-cell responsiveness to glucose.The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus.Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells.Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.
P2860
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P2860
Lipotoxicity in the pathogenesis of obesity-dependent NIDDM. Genetic and clinical implications.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Lipotoxicity in the pathogenes ...... tic and clinical implications.
@en
type
label
Lipotoxicity in the pathogenes ...... tic and clinical implications.
@en
prefLabel
Lipotoxicity in the pathogenes ...... tic and clinical implications.
@en
P356
P1433
P1476
Lipotoxicity in the pathogenes ...... tic and clinical implications.
@en
P2093
P304
P356
10.2337/DIAB.44.8.863
P407
P577
1995-08-01T00:00:00Z