Proteasome inhibition and Tau proteolysis: an unexpected regulation.
about
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processingProteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradationImplicating calpain in tau-mediated toxicity in vivo.Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions.Potential contribution of exosomes to the prion-like propagation of lesions in Alzheimer's disease.Small-molecule mediated neuroprotection in an in situ model of tauopathy.Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitorsNrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.Review: unchained maladie - a reassessment of the role of Ubb(+1) -capped polyubiquitin chains in Alzheimer's disease.The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration.The fine-tuning of proteolytic pathways in Alzheimer's disease.Tau protein degradation is catalyzed by the ATP/ubiquitin-independent 20S proteasome under normal cell conditions.Tau as a biomarker of neurodegenerative diseases.The involvement of glycogen synthase kinase-3 and protein phosphatase-2A in lactacystin-induced tau accumulation.Concentration-dependent effects of proteasomal inhibition on tau processing in a cellular model of tauopathy.NPAS4 Facilitates the Autophagic Clearance of Endogenous Tau in Rat Cortical Neurons.Tau phosphorylation affects its axonal transport and degradation.Oxidation and ubiquitination in neurodegeneration.Ubiquitin is associated with early truncation of tau protein at aspartic acid(421) during the maturation of neurofibrillary tangles in Alzheimer's disease.
P2860
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P2860
Proteasome inhibition and Tau proteolysis: an unexpected regulation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Proteasome inhibition and Tau proteolysis: an unexpected regulation.
@en
type
label
Proteasome inhibition and Tau proteolysis: an unexpected regulation.
@en
prefLabel
Proteasome inhibition and Tau proteolysis: an unexpected regulation.
@en
P2093
P2860
P1433
P1476
Proteasome inhibition and Tau proteolysis: an unexpected regulation
@en
P2093
P2860
P356
10.1016/J.FEBSLET.2004.11.018
P407
P577
2005-01-01T00:00:00Z