Inhibition of the ubiquitin-proteasome system in Alzheimer's disease. - Wikidata - wikimedia - TriplyDB

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

http://www.wikidata.org/entity/Q37387675

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Ubiquitin-proteasome system involvement in Huntington's disease Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)Histone deacetylase 6 interacts with the microtubule-associated protein tau Proximity-induced activation of human Cdc34 through heterologous dimerization.Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61 Protein phosphatases and Alzheimer's disease It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease Proteomics in Traditional Chinese Medicine with an Emphasis on Alzheimer's Disease Misframed ubiquitin and impaired protein quality control: an early event in Alzheimer's disease Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology Structural Basis of E2-25K/UBB+1 Interaction Leading to Proteasome Inhibition and Neurotoxicity Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation Functional ATPase activity of p97/valosin-containing protein (VCP) is required for the quality control of endoplasmic reticulum in neuronally differentiated mammalian PC12 cells The Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease The ubiquitin proteasome system in glia and its role in neurodegenerative diseases Top-down proteomics with mass spectrometry imaging: a pilot study towards discovery of biomarkers for neurodevelopmental disorders Prefrontal cortical and striatal transcriptional responses to the reinforcing effect of repeated methylphenidate treatment in the spontaneously hypertensive rat, animal model of attention-deficit/hyperactivity disorder (ADHD).Network-Based Analysis of Schizophrenia Genome-Wide Association Data to Detect the Joint Functional Association Signals.The modular systems biology approach to investigate the control of apoptosis in Alzheimer's disease neurodegeneration.Role of the ubiquitin proteasome system in Alzheimer's disease.Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.Aging is not associated with proteasome impairment in UPS reporter mice.Persistent hijacking of brain proteasomes in HIV-associated dementia.Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.Phosphorylation of serine 349 of p62 in Alzheimer's disease brain.Decreased Expression of α-Synuclein, Nogo-A and UCH-L1 in Patients with Schizophrenia: A Preliminary Serum Study.A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and methylmercury in mouse embryonic fibroblast.Circulating proteasome activity following mild head injury in children Gene-wide Association Study Reveals RNF122 Ubiquitin Ligase as a Novel Susceptibility Gene for Attention Deficit Hyperactivity Disorder.Relationship between tau pathology and neuroinflammation in Alzheimer's disease.Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications BimEL as a possible molecular link between proteasome dysfunction and cell death induced by mutant huntingtin Preliminary evidence of ubiquitin proteasome system dysregulation in schizophrenia and bipolar disorder: convergent pathway analysis findings from two independent samples.The ubiquitin protein catabolic disorders.Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease.β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.The biology of proteostasis in aging and disease.

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P2860

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

http://www.wikidata.org/entity/Q37387675

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on August 2000

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@en

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@nl

type

label

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@en

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@nl

prefLabel

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@en

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease

@en

P2093

A Alban

http://www.w3.org/2001/XMLSchema#string

C Jamieson

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C M Pickart

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M Landon

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R J Mayer

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R Ramage

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Y A Lam

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P2860

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

Recognition of the polyubiquitin proteolytic signal

Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes

The ubiquitin system

Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes.

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Aggresomes: a cellular response to misfolded proteins

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

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9902-9906

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scholarly article

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10.1073/PNAS.170173897

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18

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97

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Robert Layfield

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2000-08-01T00:00:00Z

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12376981

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Alzheimer's disease

ubiquitin-proteasome system

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