Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry.
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Heterotrimeric GAIT complex drives transcript-selective translation inhibition in murine macrophagesAnalysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expressionThe Ras-ERK and PI3K-mTOR pathways: cross-talk and compensationNuclear export of proteins and drug resistance in cancerRegulation of nucleocytoplasmic transport in skeletal muscle.Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors"Inhibition of PI3K/Akt pathway impairs G2/M transition of cell cycle in late developing progenitors of the avian embryo retinaPCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppressionA Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth.Inhibition of CRM1-dependent nuclear export sensitizes malignant cells to cytotoxic and targeted agentsEstrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.Vitamin E δ-tocotrienol induces p27(Kip1)-dependent cell-cycle arrest in pancreatic cancer cells via an E2F-1-dependent mechanism.A novel post-translational modification of nucleolin, SUMOylation at Lys-294, mediates arsenite-induced cell death by regulating gadd45α mRNA stability.Regulation of CDK4Distinct roles for classical nuclear import receptors in the growth of multinucleated muscle cells.Promotion of cytoplasmic mislocalization of p27 by Helicobacter pylori in gastric cancer.Nuclear import of bovine papillomavirus type 1 E1 protein is mediated by multiple alpha importins and is negatively regulated by phosphorylation near a nuclear localization signal.Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitorsProbing the nuclear import signal and nuclear transport molecular determinants of PRV ICP22The B56γ3 regulatory subunit-containing protein phosphatase 2A outcompetes Akt to regulate p27KIP1 subcellular localization by selectively dephosphorylating phospho-Thr157 of p27KIP1.S10 phosphorylation of p27 mediates atRA induced growth arrest in ovarian carcinoma cell lines.Radiation-induced EGFR-signaling and control of DNA-damage repair.Nuclear and mitochondrial signalling Akts in cardiomyocytesInhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancerThe function of p27 KIP1 during tumor development.Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.AKT1 induces caspase-mediated cleavage of the CDK inhibitor p27Kip1 during cell cycle progression in leukemia cells transformed by FLT3-ITD.Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood.An ERBB3/ERBB2 oncogenic unit plays a key role in NRG1 signaling and melanoma cell growth and survival.Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.Ceramide produces apoptosis through induction of p27(kip1) by protein phosphatase 2A-dependent Akt dephosphorylation in PC-3 prostate cancer cells.PP2A interaction with Rb2/p130 mediates translocation of Rb2/p130 into the nucleus in all-trans retinoic acid-treated ovarian carcinoma cells.AKT1 mediates bypass of the G1/S checkpoint after genotoxic stress in normal human cells.Down-regulation of Notch-dependent transcription by Akt in vitro.A nuclear export signal and phosphorylation regulate Dok1 subcellular localization and functionsTwo populations of p27 use differential kinetics to phosphorylate Ser-10 and Thr-187 via phosphatidylinositol 3-Kinase in response to fibroblast growth factor-2 stimulation.Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.
P2860
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P2860
Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Phosphorylation of p27Kip1 at ...... and prevents nuclear re-entry.
@en
type
label
Phosphorylation of p27Kip1 at ...... and prevents nuclear re-entry.
@en
prefLabel
Phosphorylation of p27Kip1 at ...... and prevents nuclear re-entry.
@en
P2093
P2860
P356
P1476
Phosphorylation of p27Kip1 at ...... and prevents nuclear re-entry.
@en
P2093
Carlos L Arteaga
Frederick Y Wu
Incheol Shin
Jeremy Rotty
P2860
P304
P356
10.1074/JBC.M412367200
P407
P577
2004-12-03T00:00:00Z