Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells.
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Akt binds to and phosphorylates phospholipase C-gamma1 in response to epidermal growth factorAkt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCDCa(2+)/calmodulin directly interacts with the pleckstrin homology domain of AKT1.Antiplatelet Activity of a Newly Synthesized Novel Ruthenium (II): A Potential Role for Akt/JNK SignalingScanning the human proteome for calmodulin-binding proteins.Disruption of sarcolemmal ATP-sensitive potassium channel activity impairs the cardiac response to systolic overload.Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.Pnck induces ligand-independent EGFR degradation by probable perturbation of the Hsp90 chaperone complex.Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-xL strategies through Mcl-1 down-regulation.Molecular cloning and expression of the calmodulin gene from guinea pig hearts.Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition.Influence maximization in time bounded network identifies transcription factors regulating perturbed pathwaysStructural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt.A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis.Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradationTrans-resveratrol boronic acid exhibits enhanced anti-proliferative activity on estrogen-dependent MCF-7 breast cancer cellsThe basal level of intracellular calcium gates the activation of phosphoinositide 3-kinase-Akt signaling by brain-derived neurotrophic factor in cortical neuronsCalmodulin modulates Akt activity in human breast cancer cell lines.alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.Endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest and apoptosis through down-regulation of the phosphatidylinositide 3-kinase/Akt/HDM2 pathway.Mitochondrial DNA depletion sensitizes cancer cells to PARP inhibitors by translational and post-translational repression of BRCA2.PTEN-mediated ERK1/2 inhibition and paradoxical cellular proliferation following Pnck overexpression.Calcium deficiency-induced and TRP channel-regulated IGF1R-PI3K-Akt signaling regulates abnormal epithelial cell proliferationLipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes.TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells.K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target?KCa1.1 channels regulate β1-integrin function and cell adhesion in rheumatoid arthritis fibroblast-like synoviocytes.Platelet-derived growth factor-BB activates calcium/calmodulin-dependent and -independent mechanisms that mediate Akt phosphorylation in the neurofibromin-deficient human Schwann cell line ST88-14Significance of calcium binding, tyrosine phosphorylation, and lysine trimethylation for the essential function of calmodulin in vertebrate cells analyzed in a novel gene replacement system.Ca(2+) /calmodulin- dependent protein kinase II mediates transforming growth factor-β-induced hepatic stellate cells proliferation but not in collagen α1(I) production.Differential effects of calcium on PI3K-Akt and HIF-1α survival pathways.Ecdysteroids elicit a rapid Ca2+ flux leading to Akt activation and increased protein synthesis in skeletal muscle cells.Calmodulin inhibition contributes to sensitize TRAIL-induced apoptosis in human lung cancer H1299 cells.Akt and mitogen-activated protein kinase enhance C-type lectin-like receptor 2-mediated platelet activation by inhibition of glycogen synthase kinase 3α/β.Targeting the signaling pathway of acylation stimulating protein.ATP2B1 gene Silencing Increases Insulin Sensitivity through Facilitating Akt Activation via the Ca2+/calmodulin Signaling Pathway and Ca2+-associated eNOS Activation in Endothelial Cells.CBP501 inhibits EGF-dependent cell migration, invasion and epithelial-to-mesenchymal transition of non-small cell lung cancer cells by blocking KRas to calmodulin binding.The Interplay between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt.Akt activation by Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) in ovarian cancer cells.
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P2860
Calmodulin-mediated activation of Akt regulates survival of c-Myc-overexpressing mouse mammary carcinoma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Calmodulin-mediated activation ...... mouse mammary carcinoma cells.
@en
type
label
Calmodulin-mediated activation ...... mouse mammary carcinoma cells.
@en
prefLabel
Calmodulin-mediated activation ...... mouse mammary carcinoma cells.
@en
P2093
P2860
P356
P1476
Calmodulin-mediated activation ...... mouse mammary carcinoma cells.
@en
P2093
Christine M Coticchia
Robert B Dickson
Tushar B Deb
P2860
P304
38903-38911
P356
10.1074/JBC.M405314200
P407
P577
2004-07-09T00:00:00Z