Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.
about
The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter traffickingProtein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neuronsGABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRETExpression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6.Dopamine transporter trafficking: rapid response on demand.Ethanol alters endosomal recycling of human dopamine transporters.Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton.Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption.Concentrative export from the endoplasmic reticulum of the gamma-aminobutyric acid transporter 1 requires binding to SEC24D.N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo.Manganese nanoparticle activates mitochondrial dependent apoptotic signaling and autophagy in dopaminergic neuronal cellsThree ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporterα-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.Brain Region-Specific Trafficking of the Dopamine Transporter.Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter traffickingA conserved hydrophobic tetrad near the C terminus of the secretory Na+-K+-2Cl- cotransporter (NKCC1) is required for its correct intracellular processing.Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness.Trafficking of dopamine transporters in psychostimulant actions.Two novel functions of hyaluronidase-2 (Hyal2) are formation of the glycocalyx and control of CD44-ERM interactionsCtr9, a Protein in the Transcription Complex Paf1, Regulates Dopamine Transporter Activity at the Plasma Membrane.Calcium dependent interaction of calmodulin with the GlyT1 C-terminus.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.C-terminal region regulates the functional expression of human noradrenaline transporter splice variants.Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.Dopamine transporter is enriched in filopodia and induces filopodia formation.Glycine transporter dimers: evidence for occurrence in the plasma membrane.A dopamine transporter mutation associated with bipolar affective disorder causes inhibition of transporter cell surface expression.Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C.Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.Diacidic motifs influence the export of transmembrane proteins from the endoplasmic reticulum in plant cells.
P2860
Q28115330-88AFF673-9DE6-4316-85CF-4AD4C52AF951Q28567412-511DDBA7-DFC9-4EB2-8AE0-4CB05D85F902Q33590316-0D163734-5D4F-4946-9C93-2EE4AD71D893Q33654253-ECE4C84D-665F-475D-B82E-8B94B8858B4DQ33654916-8DB3A108-424A-4EA6-A1BF-B38DDCA5256BQ33795986-738AC025-12B4-48E8-A6BE-CB9132875DD3Q34383082-48C335F1-D143-4BBD-B085-99226E653B07Q34513168-21E99173-1D28-4115-953F-5629B03526DFQ34599412-7537A0B3-F3D0-4B1D-AD55-EAE6546FDCA2Q35091143-29170C17-A4EE-4B57-875B-68DEDA2B3F3FQ35489449-88B1FB01-324D-4A1D-95E1-93F87A39F234Q35545334-72AD70CD-A267-401A-ACCD-59CDAC64272CQ35626155-83F91C2A-72A9-4790-A7FF-313B58859F30Q36064414-42AC0182-0BA3-4823-B871-BA179EEFEBBDQ36739955-6A9BC2BF-8D93-4F62-BAF0-F964CFC3D052Q37119826-4E750AB7-91F9-48BF-B728-580999F73F85Q37141267-364F50E2-57F2-4395-9D44-D47B1C13AB12Q37533305-61F18952-DB52-44C1-A543-B45AEB2D531BQ38350133-E1192CAF-15EA-4E03-902A-66FFAD4DC3DAQ38866802-FE86D185-6C54-4941-9AB6-A8819161D352Q38962081-C92A3158-BFD0-4B6D-BA49-80B9DD2913DFQ39459667-20E9F654-43CC-4FAE-9D16-8170CC0DC145Q40233384-BB09E541-20FE-4F7C-A267-BB52B90338E2Q41175275-E3F8B4D6-39EA-4248-B7ED-8419A673BFD9Q41337842-C3D9A32C-DBD2-49AA-99B5-502EB7DFDB3FQ41658029-E3E57D33-5FD1-4B43-BF00-2943F82A3FD7Q46653202-7C3A13D2-29EF-412B-8039-EBCB2F323065Q46658258-86A3DDDD-57B7-44EF-8408-841AD3FABF49Q47622230-73C76B8A-81EC-4A62-8144-0FE5E1E6D111Q52566483-D5724250-F3BC-4397-88AC-38B36D8A2889
P2860
Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Multiple molecular determinant ...... rt from endoplasmic reticulum.
@en
type
label
Multiple molecular determinant ...... rt from endoplasmic reticulum.
@en
prefLabel
Multiple molecular determinant ...... rt from endoplasmic reticulum.
@en
P2093
P2860
P356
P1476
Multiple molecular determinant ...... ort from endoplasmic reticulum
@en
P2093
Alexander Sorkin
Manuel Miranda
Tatiana Sorkina
W Michael Zawada
P2860
P304
30760-30770
P356
10.1074/JBC.M312774200
P407
P577
2004-05-05T00:00:00Z