RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
about
Cullin-RING ubiquitin ligases: global regulation and activation cyclesStructural basis of selective ubiquitination of TRF1 by SCFFbx4RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport.The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cellsBTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligaseKeap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.DBC2 is essential for transporting vesicular stomatitis virus glycoproteinDBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradationCyclin D1 down-regulation is essential for DBC2's tumor suppressor functionSequence and structural analysis of BTB domain proteinsAtypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and TumorigenesisStructural Mechanisms and Drug Discovery Prospects of Rho GTPasesBood POZ containing gene type 2 is a human counterpart of yeast Btb3p and promotes the degradation of terminal deoxynucleotidyltransferaseConstitutive turnover of cyclin E by Cul3 maintains quiescenceHsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complexX-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionExpression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strainOxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness.BPOZ-2 directly binds to eEF1A1 to promote eEF1A1 ubiquitylation and degradation and prevent translation.Arabidopsis has two redundant Cullin3 proteins that are essential for embryo development and that interact with RBX1 and BTB proteins to form multisubunit E3 ubiquitin ligase complexes in vivo.A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.DBC2/RhoBTB2 functions as a tumor suppressor protein via Musashi-2 ubiquitination in breast cancerA CULLINary ride across the secretory pathway: more than just secretion.The emerging role of the COP9 signalosome in cancer.SCF E3 ubiquitin ligases as anticancer targets.Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors.The tumor suppressor RhoBTB1 controls Golgi integrity and breast cancer cell invasion through METTL7B.Cullin-3 protein expression levels correlate with breast cancer progression.Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases.Evaluation of Methylation Status in the 5'UTR Promoter Region of the DBC2 Gene as a Biomarker in Sporadic Breast CancerRho5p is involved in mediating the osmotic stress response in Saccharomyces cerevisiae, and its activity is regulated via Msi1p and Npr1p by phosphorylation and ubiquitination.Rho GTPases of the RhoBTB subfamily and tumorigenesis.RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse embryogenesis and cancer cell survival.Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism.Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.Role of E3 ubiquitin ligases in lung cancer.Rho GTPases and cancer.The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells.RhoBTB2 (DBC2) is a mitotic E2F1 target gene with a novel role in apoptosis.
P2860
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P2860
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
description
2004 nî lūn-bûn
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2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
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2004年论文
@wuu
2004年论文
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2004年论文
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name
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
@en
type
label
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
@en
prefLabel
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
@en
P2093
P2860
P356
P1433
P1476
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
@en
P2093
Andrew Wilkins
Christopher L Carpenter
Qinggong Ping
P2860
P304
P356
10.1101/GAD.1177904
P577
2004-04-01T00:00:00Z