The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals.
about
The role of viral persistence in flavivirus biologyStructure and functionality in flavivirus NS-proteins: perspectives for drug designStructural proteomics of dengue virusThe Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates SplicingA crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replicationThe C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus ProductionStructure of the Dengue Virus Helicase/Nucleoside Triphosphatase Catalytic Domain at a Resolution of 2.4 ANuclear Localization of Flavivirus RNA Synthesis in Infected CellsProbing the substrate specificity of the dengue virus type 2 NS3 serine protease by using internally quenched fluorescent peptidesCrystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionThe Two-component NS2B-NS3 Proteinase Represses DNA Unwinding Activity of the West Nile Virus NS3 HelicaseGlyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3' ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 proteinCRM1-mediated Nuclear Export of Dengue Virus RNA Polymerase NS5 Modulates Interleukin-8 Induction and Virus ProductionCrystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interfaceDownregulation of Aedes aegypti chromodomain helicase DNA binding protein 7/Kismet by Wolbachia and its effect on dengue virus replicationHigh affinity human antibody fragments to dengue virus non-structural protein 3Identification of new protein interactions between dengue fever virus and its hosts, human and mosquitoA viral-human interactome based on structural motif-domain interactions captures the human infectomePerturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongationThe IMPORTance of the Nucleus during Flavivirus Replication.Spatiotemporal dynamics and epistatic interaction sites in dengue virus type 1: a comprehensive sequence-based analysis.A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in miceComparative analysis of full-length genomic sequences of 10 dengue serotype 1 viruses associated with different genotypes, epidemics, and disease severity isolated in Thailand over 22 yearsThe interferon signaling antagonist function of yellow fever virus NS5 protein is activated by type I interferonComparative expression profiles of midgut genes in dengue virus refractory and susceptible Aedes aegypti across critical period for virus infection.The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replicationProfiling of viral proteins expressed from the genomic RNA of Japanese encephalitis virus using a panel of 15 region-specific polyclonal rabbit antisera: implications for viral gene expression.A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral ReplicationPoint mutations in the West Nile virus (Flaviviridae; Flavivirus) RNA-dependent RNA polymerase alter viral fitness in a host-dependent manner in vitro and in vivoMouse STAT2 restricts early dengue virus replicationNuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling.Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pHMolecular aspects of Dengue virus replication.Genome cyclization as strategy for flavivirus RNA replicationSerotype-specific differences in dengue virus non-structural protein 5 nuclear localizationReplication cycle and molecular biology of the West Nile virus.Regulation of flavivirus RNA synthesis and capping.Organization of the Flavivirus RNA replicase complex.Functional interplay among the flavivirus NS3 protease, helicase, and cofactors.Genomics, proteomics and evolution of dengue virus.
P2860
Q22809893-1CB8FEBB-2D19-430C-B664-27CE5E537BD6Q23011530-8594A4CA-7282-45F4-9370-67D030B07AC0Q24658386-46F9A75D-A482-4152-8E03-1649AC9CF727Q26970797-486D3345-8180-43D4-8D4E-4248135DFC5BQ27321114-A8C0CAB7-9A48-4EAB-9B61-AF00D601E7F5Q27468720-5FA7B1C5-D366-49F3-91F6-E34D9544BA2AQ27470453-31A6737D-C446-4437-B2C3-4A3C1C9FFAB7Q27473225-97160763-AC5A-4B87-9E1C-9CA556826573Q27473256-0DE564DC-F4C9-4573-B14E-A476B66315BBQ27480349-DAC42AC9-CB0C-407D-829A-BE5A1728D340Q27486257-1F370F79-336D-410E-B83C-D9D3883EBAB6Q27488343-6B22FA28-3022-4E09-938D-7D06FC7DAD66Q27488888-C318B62B-8153-49A6-9B2A-549DBF45E36FQ27679697-D9CC8210-172B-403C-B40C-CBA775D0B13CQ27928001-356AC364-DE0B-4176-AFA5-9761452FFA3BQ28476043-CF3AE9DA-F05B-407D-95C4-064908E7D9DCQ28485040-6D7CCD31-DE5B-4F0F-87A2-A7E49BA2C4D0Q28535207-0870ADFF-8776-4F08-A158-234B397DBFF4Q28651848-5BBBADDE-BFCA-4816-9A6E-6F92C77AA69DQ30238914-40BCA084-B747-4BA5-AE1C-74BF1688198EQ31139537-FF667537-7B29-48B7-936A-89C1B3B24841Q33602692-5179579A-1A00-4EE4-9612-02908153974FQ34240187-D3BCF0A4-FBF0-4EA4-8AAD-74B0E3E4CEE2Q34251294-D4749F61-FC3A-4DEB-B23F-65C60C4CAD4AQ34450750-6F8158A9-06D1-4009-9228-0F4BE9CD05C9Q35002993-F77E82B8-5555-419D-A8A5-96EBE51A67E6Q35542073-4AF5DBC2-B061-4EA3-AD7E-DA8A0E70DFBAQ35758578-B9E7F634-6E01-43E0-A3C4-B7F9B5838A59Q35823089-2819A5CF-4AC1-48EC-80F3-6E9B39BE03DAQ35846922-99F59362-FA57-46E3-ADE8-281D27F2F2D1Q36760135-34EBD7BC-B87D-4E38-8D2B-9FAC7EE21508Q36950920-945D2DCE-17A3-44E1-8291-62B510134D1FQ37119034-D67DDD02-572D-4542-8C0B-A1F4BA2983C6Q37243494-03FC68B4-00EE-417A-89FF-DB4682096404Q37311934-6A432977-5847-4695-AE24-3899FD7077D2Q37566687-C2AF35D4-3A99-43DA-BD79-06D1CA7B6378Q38127643-C940CEAC-89C9-4854-A69C-0290384A679DQ38156710-6467A243-929D-4AF3-B5F6-EE6B8DF78127Q38201317-6F3F209F-B3FD-4E80-8A4F-A14D4B3D23FFQ39078484-2296B679-089A-4B06-A678-154D069A7470
P2860
The interdomain region of dengue NS5 protein that binds to the viral helicase NS3 contains independently functional importin beta 1 and importin alpha/beta-recognized nuclear localization signals.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The interdomain region of deng ...... nuclear localization signals.
@en
type
label
The interdomain region of deng ...... nuclear localization signals.
@en
prefLabel
The interdomain region of deng ...... nuclear localization signals.
@en
P2093
P2860
P356
P1476
The interdomain region of deng ...... nuclear localization signals.
@en
P2093
Anna V John
David A Jans
Magnus Johansson
Subhash G Vasudevan
P2860
P304
36399-36407
P356
10.1074/JBC.M204977200
P407
P577
2002-06-24T00:00:00Z