Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase.
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Pathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addictionAlternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedEndometrial cancer side-population cells show prominent migration and have a potential to differentiate into the mesenchymal cell lineagePotential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy.RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cellsMet-related receptor tyrosine kinase Ron in tumor growth and metastasis.Crosstalk between Smad and Mitogen-Activated Protein Kinases for the Regulation of Apoptosis in Cyclosporine A- Induced Renal Tubular Injury.Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.Residual tumor cells that drive disease relapse after chemotherapy do not have enhanced tumor initiating capacity.Isolation of Fully Human Antagonistic RON Antibodies Showing Efficient Block of Downstream Signaling and Cell Migration.Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networksHuman RON receptor tyrosine kinase induces complete epithelial-to-mesenchymal transition but causes cellular senescence.Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating proteinThe monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.Ron receptor overexpression in the murine prostate induces prostate intraepithelial neoplasia.The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humansOncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers.Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signalingSignificance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells.RON kinase isoforms demonstrate variable cell motility in normal cells.Transformation of madin-darby canine kidney epithelial cells by sheep retrovirus envelope proteins.Recepteur d'origine nantais (RON), more than a kinase: Role in castrate-resistant prostate cancer.Smad4-dependent TGF-beta signaling suppresses RON receptor tyrosine kinase-dependent motility and invasion of pancreatic cancer cells.Macrophage stimulating protein promotes liver metastases of small cell lung cancer cells by affecting the organ microenvironment.Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway.Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain.Transforming growth factor-beta1 modulates metalloproteinase-2 and -9, nitric oxide, RhoA and alpha-smooth muscle actin expression in colon adenocarcinoma cells.Knockdown of Ron kinase inhibits mutant phosphatidylinositol 3-kinase and reduces metastasis in human colon carcinoma.Mechanisms of cytoplasmic {beta}-catenin accumulation and its involvement in tumorigenic activities mediated by oncogenic splicing variant of the receptor originated from Nantes tyrosine kinase.RON Signaling Is a Key Mediator of Tumor Progression in Many Human Cancers.Decoding a cancer-relevant splicing decision in the RON proto-oncogene using high-throughput mutagenesismTORC1 is a key mediator of RON-dependent breast cancer metastasis with therapeutic potential
P2860
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P2860
Collaborative activities of macrophage-stimulating protein and transforming growth factor-beta1 in induction of epithelial to mesenchymal transition: roles of the RON receptor tyrosine kinase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Collaborative activities of ma ...... RON receptor tyrosine kinase.
@en
type
label
Collaborative activities of ma ...... RON receptor tyrosine kinase.
@en
prefLabel
Collaborative activities of ma ...... RON receptor tyrosine kinase.
@en
P2093
P2860
P356
P1433
P1476
Collaborative activities of ma ...... RON receptor tyrosine kinase.
@en
P2093
Ming-Hai Wang
Yi-Qing Chen
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207282
P407
P577
2004-03-01T00:00:00Z
P5875
P6179
1001625975