Molecular determinants of vanilloid sensitivity in TRPV1.
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Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonistsTRPV1: a target for next generation analgesicsTRPV1: on the road to pain reliefPhysiology and pharmacology of the vanilloid receptorEffects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)Acidification of rat TRPV1 alters the kinetics of capsaicin responses.TRP channels in schistosomesTRP Channels as Therapeutic Targets in Diabetes and ObesityIntegrating TRPV1 Receptor Function with Capsaicin PsychophysicsFunctionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational dataTRPV1 and SP: key elements for sepsis outcome?Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoniDetailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational StudyTRPV1 structures in distinct conformations reveal activation mechanismsDifferential Activation of TRP Channels in the Adult Rat Spinal Substantia Gelatinosa by Stereoisomers of Plant-Derived ChemicalsThe vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neuronsTRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid actionExploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screeningEngineering vanilloid-sensitivity into the rat TRPV2 channelTRPV1 ligands with hyperthermic, hypothermic and no temperature effects in ratsImplications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing DomainReactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neuronsDrug-induced mild therapeutic hypothermia obtained by administration of a transient receptor potential vanilloid type 1 agonist.Nicotinic acid activates the capsaicin receptor TRPV1: Potential mechanism for cutaneous flushing.Structure-functional intimacies of transient receptor potential channels.A bivalent tarantula toxin activates the capsaicin receptor, TRPV1, by targeting the outer pore domainCapsazepine is a novel activator of the delta subunit of the human epithelial Na+ channel.Molecular basis determining inhibition/activation of nociceptive receptor TRPA1 protein: a single amino acid dictates species-specific actions of the most potent mammalian TRPA1 antagonist.Structure-activity relationship of capsaicin analogs and transient receptor potential vanilloid 1-mediated human lung epithelial cell toxicity.Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications.The expanding field of cannabimimetic and related lipid mediators.Desensitization of transient receptor potential ankyrin 1 (TRPA1) by the TRP vanilloid 1-selective cannabinoid arachidonoyl-2 chloroethanolamineUnveiling TRPV1 spatio-temporal organization in live cell membranes.Acid-sensitive ion channels and receptorsCapsaicin interaction with TRPV1 channels in a lipid bilayer: molecular dynamics simulation.Modality-specific mechanisms of protein kinase C-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site.Molecular cloning and functional characterization of Xenopus tropicalis frog transient receptor potential vanilloid 1 reveal its functional evolution for heat, acid, and capsaicin sensitivities in terrestrial vertebrates.Structural mechanism underlying capsaicin binding and activation of the TRPV1 ion channel.Intact microtubules preserve transient receptor potential vanilloid 1 (TRPV1) functionality through receptor bindingStructural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations.
P2860
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P2860
Molecular determinants of vanilloid sensitivity in TRPV1.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Molecular determinants of vanilloid sensitivity in TRPV1.
@en
type
label
Molecular determinants of vanilloid sensitivity in TRPV1.
@en
prefLabel
Molecular determinants of vanilloid sensitivity in TRPV1.
@en
P2093
P356
P1476
Molecular determinants of vanilloid sensitivity in TRPV1.
@en
P2093
Attila Toth
Frank Porreca
James J S Treanor
Jean-Claude Louis
Lana Klionsky
Larry V Pearce
Licheng Shi
Narender R Gavva
P304
20283-20295
P356
10.1074/JBC.M312577200
P407
P577
2004-03-02T00:00:00Z