Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
about
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus.Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNALength-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 55'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-ISmall dsRNAs induce transcriptional activation in human cellssiRNA target site secondary structure predictions using local stable substructuresHost gene targets for novel influenza therapies elucidated by high-throughput RNA interference screensInterferon induction by RNA viruses and antagonism by viral pathogensIrf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infectionSystems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivityThe response of mammalian cells to double-stranded RNAThe RNA-activated Protein Kinase Enhances the Induction of Interferon- and Apoptosis Mediated by Cytoplasmic RNA SensorsInvestigating a New Generation of Ribozymes in Order to Target HCVInfluenza virus activation of the interferon systemRNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cellsProgress toward in vivo use of siRNAs-IIInhibition of cell proliferation by an anti-EGFR aptamer5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication.Immunostimulatory motifs enhance antiviral siRNAs targeting highly pathogenic avian influenza H5N1.Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnologyRNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cellsComplete, gene-specific siRNA libraries: production and expression in mammalian cells.Genome-wide application of RNAi to the discovery of potential drug targets.Cytosolic 5'-triphosphate ended viral leader transcript of measles virus as activator of the RIG I-mediated interferon responseAnalysis of siRNA specificity on targets with double-nucleotide mismatchesOff-target effects of siRNA specific for GFPRNAi methodologies for the functional study of signaling moleculesDesigner siRNAs to overcome the challenges from the RNAi pathway.Sequence-non-specific effects of RNA interference triggers and microRNA regulators.Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs.Advancement and prospects of tumor gene therapySimultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth.Selection of potent non-toxic inhibitory sequences from a randomized HIV-1 specific lentiviral short hairpin RNA library.Early lethality of shRNA-transgenic pigs due to saturation of microRNA pathwaysRIG-I is required for the inhibition of measles virus by retinoidsHigh-dose siRNAs upregulate mouse Eri-1 at both transcription and posttranscription levelsDouble-stranded RNA induces sequence-specific antiviral silencing in addition to nonspecific immunity in a marine shrimp: convergence of RNA interference and innate immunity in the invertebrate antiviral response?Infection-dependent nuclear localization of US17, a member of the US12 family of human cytomegalovirus-encoded seven-transmembrane proteins.Unlocking the potential of the human genome with RNA interference.Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.
P2860
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P2860
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
@en
type
label
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
@en
prefLabel
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
@en
P2093
P356
P1433
P1476
Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase.
@en
P2093
Dong-Ho Kim
Edouard Cantin
John J Rossi
Michael Longo
Patric Lundberg
P2888
P304
P356
10.1038/NBT940
P577
2004-02-08T00:00:00Z
P5875
P6179
1027137315