Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.
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FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complexMembrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumorsGolgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogenDevelopment of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinasesCells assemble invadopodia-like structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assayProtective effect of bisphosphonates on endometrial cancer incidence in data from the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial.The role of matrix metalloproteinase in the intimal sarcoma-like cells derived from endarterectomized tissues from a chronic thromboembolic pulmonary hypertension patientCollagen I but not Matrigel matrices provide an MMP-dependent barrier to ovarian cancer cell penetration.Peptide aptamers as new tools to modulate clathrin-mediated internalisation--inhibition of MT1-MMP internalisation.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?High-affinity peptide against MT1-MMP for in vivo tumor imagingHelicobacter pylori promote gastric cancer cells invasion through a NF-kappaB and COX-2-mediated pathwayTargeting tumor cell motility to prevent metastasis.17-AAG suppresses growth and invasion of lung adenocarcinoma cells via regulation of the LATS1/YAP pathway.Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase.In vivo optical imaging of membrane-type matrix metalloproteinase (MT-MMP) activityLack of Association between Membrane-Type 1 Matrix Metalloproteinase Expression and Clinically Relevant Molecular or Morphologic Tumor Characteristics at the Leading Edge of Invasive Colorectal Carcinoma.Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinomaInvasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex.Targeting Matrix Metalloproteinases in Cancer: Bringing New Life to Old IdeasCD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity.Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMPRe-expression of miR-200 by novel approaches regulates the expression of PTEN and MT1-MMP in pancreatic cancer.MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells.The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.Tumour endoproteases: the cutting edge of cancer drug delivery?URG11 promotes gastric cancer growth and invasion by activation of beta-catenin signalling pathway.Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer.Self-organization of engineered epithelial tubules by differential cellular motility.Development of novel tumor-targeted theranostic nanoparticles activated by membrane-type matrix metalloproteinases for combined cancer magnetic resonance imaging and therapySelective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer.Extracellular matrix determinants and the regulation of cancer cell invasion stratagems.MicroRNA-524-5p suppresses the growth and invasive abilities of gastric cancer cellsInhibiting the SUMO Pathway Represses the Cancer Stem Cell Population in Breast and Colorectal CarcinomasEstablishment and characterization of a new feline mammary cancer cell line, FkMTp.AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival.Pioglitazone, a PPARγ agonist, inhibits growth and invasion of human hepatocellular carcinoma via blockade of the rage signaling.Knockdown of RAGE inhibits growth and invasion of gastric cancer cells.The role and clinical significance of YES-associated protein 1 in human osteosarcoma.YES-associated protein 1 promotes adenocarcinoma growth and metastasis through activation of the receptor tyrosine kinase Axl.
P2860
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P2860
Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Sequence-specific silencing of ...... ic target for invasive tumors.
@en
type
label
Sequence-specific silencing of ...... ic target for invasive tumors.
@en
prefLabel
Sequence-specific silencing of ...... ic target for invasive tumors.
@en
P2093
P2860
P356
P1433
P1476
Sequence-specific silencing of ...... ic target for invasive tumors.
@en
P2093
Junko Ueda
Katsuyuki Fujii
Masahiro Kajita
Motoharu Seiki
Naoko Suenaga
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206962
P407
P577
2003-11-01T00:00:00Z
P5875
P6179
1024522195