Improved system for helper-dependent adenoviral vector production.
about
A complementation method for functional analysis of mammalian genesNeuroanatomy goes viral!The adenovirus genome contributes to the structural stability of the virionGene therapy: light is finally in the tunnelThe role of chromatin in adenoviral vector functionGutless adenovirus: last-generation adenovirus for gene therapyScalable production in human cells and biochemical characterization of full-length normal and mutant huntingtinHuman gene therapy and imaging in neurological diseases.Helper-dependent adenoviral gene therapy mediates long-term correction of the clotting defect in the canine hemophilia A model.Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors.Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccinesVector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.TFE3 regulates whole-body energy metabolism in cooperation with TFEB.Adenoviral Vectors for Hemophilia Gene TherapyLarge-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories.In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector.Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primatesInhibition of hepatitis B virus replication by helper dependent adenoviral vectors expressing artificial anti-HBV pri-miRs from a liver-specific promoter.Bioengineered factor IX molecules with increased catalytic activity improve the therapeutic index of gene therapy vectors for hemophilia BMyD88-dependent silencing of transgene expression during the innate and adaptive immune response to helper-dependent adenovirus.Altering the Ad5 packaging domain affects the maturation of the Ad particles.Mutations in the BRCT binding site of BRCA1 result in hyper-recombinationLiver-directed gene therapy for dyslipidemia and diabetesVasoactive intestinal peptide increases hepatic transduction and reduces innate immune response following administration of helper-dependent Ad.Induction of type I interferon by adenovirus-encoded small RNAs.Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses.Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease.Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B.Infectivity-selective oncolytic adenovirus developed by high-throughput screening of adenovirus-formatted libraryModifications of adenovirus hexon allow for either hepatocyte detargeting or targeting with potential evasion from Kupffer cellsHuman chromosome 2 carries a gene required for production of infectious human immunodeficiency virus type 1.Neonatal helper-dependent adenoviral vector gene therapy mediates correction of hemophilia A and tolerance to human factor VIIICharacterization of species C human adenovirus serotype 6 (Ad6)Correction of hyperbilirubinemia in gunn rats using clinically relevant low doses of helper-dependent adenoviral vectorsHost inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection.Gene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector.Quantification of high-capacity helper-dependent adenoviral vector genomes in vitro and in vivo, using quantitative TaqMan real-time polymerase chain reaction.Generation of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer.Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells.SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction.
P2860
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P2860
Improved system for helper-dependent adenoviral vector production.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Improved system for helper-dependent adenoviral vector production.
@en
type
label
Improved system for helper-dependent adenoviral vector production.
@en
prefLabel
Improved system for helper-dependent adenoviral vector production.
@en
P1433
P1476
Improved system for helper-dependent adenoviral vector production.
@en
P2093
Donna Palmer
P304
P356
10.1016/J.YMTHE.2003.08.014
P577
2003-11-01T00:00:00Z