Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
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Recent advances in understanding multiple myelomaTowards Stratified Medicine in Plasma Cell MyelomaThe myeloma stem cell concept, revisited: from phenomenology to operational termsAdvances in understanding prognosis in myeloma.Chromosome 1 amplification has similar prognostic value to del(17p13) and t(4;14)(p16;q32) in multiple myeloma patients: analysis of real-life data from the Polish Myeloma Study Group.The varied distribution and impact of RAS codon and other key DNA alterations across the translocation cyclin D subgroups in multiple myelomaSearch for rare protein altering variants influencing susceptibility to multiple myelomaMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.Cutting edge genomics reveal new insights into tumour development, disease progression and therapeutic impacts in multiple myeloma.Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma.Clinical value of molecular subtyping multiple myeloma using gene expression profilingTreatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group.A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma.The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma.Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma.Kinase inhibitors as potential agents in the treatment of multiple myeloma.Recurrent mutations of MAPK pathway genes in multiple myeloma but not in amyloid light-chain amyloidosis.Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker.Monitoring multiple myeloma by quantification of recurrent mutations in serum.Logic programming reveals alteration of key transcription factors in multiple myeloma.Neutral tumor evolution in myeloma is associated with poor prognosis.Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma.Quantitative PCR: an alternative approach to detect common copy number alterations in multiple myeloma.Utilizing next-generation sequencing in the management of multiple myeloma.Panel sequencing for clinically oriented variant screening and copy number detection in 142 untreated multiple myeloma patients.Immunologic approaches for the treatment of multiple myeloma.Overexpression of B-cell lymphoma 6 alters gene expression profile in a myeloma cell line and is associated with decreased DNA damage response.IQGAP1 Scaffold-MAP Kinase Interactions Enhance Multiple Myeloma Clonogenic Growth and Self-Renewal.Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1905 trial patients.The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma.Next-generation sequencing of a family with a high penetrance of monoclonal gammopathies for the identification of candidate risk alleles.The Mutational Landscape of Circulating Tumor Cells in Multiple Myeloma.Management of high-risk Myeloma: an evidence-based review of treatment strategies.Current Review on High-Risk Multiple Myeloma.Clinical Trials in the Genomic Era.Mutational landscape reflects the biological continuum of plasma cell dyscrasias.RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response.Epigenetic regulatory mutations and epigenetic therapy for multiple myeloma.Diagnosis and classification of hematologic malignancies on the basis of genetics.
P2860
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P2860
Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en-gb
type
label
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en-gb
prefLabel
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en
Mutational Spectrum, Copy Numb ...... With Newly Diagnosed Myeloma.
@en-gb
P2093
P50
P356
P1154
2-s2.0-84947116451
P1476
Mutational Spectrum, Copy Numb ...... s With Newly Diagnosed Myeloma
@en
P2093
Alex Murison
Aneta Mikulasova
David A Cairns
David C Johnson
Dil B Begum
Fabio Mirabella
Faith E Davies
Graham H Jackson
John R Jones
Lauren I Aronson
P304
P356
10.1200/JCO.2014.59.1503
P407
P50
P5530
P577
2015-08-17T00:00:00Z
P6179
1005350338