Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
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Cbl-mediated degradation of Lyn and Fyn induced by constitutive fibroblast growth factor receptor-2 activation supports osteoblast differentiationNovel RING E3 ubiquitin ligases in breast cancerAbi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosisUbiquitylation of leptin receptor OB-Ra regulates its clathrin-mediated endocytosisUbiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisRegulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8·STAM complexc-Cbl-dependent monoubiquitination and lysosomal degradation of gp130Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradationA tale of two Cbls: interplay of c-Cbl and Cbl-b in epidermal growth factor receptor downregulationUbiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomesProtein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligasesEGFR ligands exhibit functional differences in models of paracrine and autocrine signalingDisabled1 regulates the intracellular trafficking of reelin receptorsThe Cbl interactome and its functionsThe ubiquitin-proteasome system in spongiform degenerative disordersLipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptorsRegulation of epidermal growth factor receptor down-regulation by UBPY-mediated deubiquitination at endosomesCbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pitsTULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin.Clathrin-independent endocytosis of ErbB2 in geldanamycin-treated human breast cancer cells.Cbl controls EGFR fate by regulating early endosome fusion.Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function.The ubiquitination code: a signalling problem.Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loopD-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis.Clathrin-independent endocytosis of ubiquitinated cargosThe von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.Heterozygous germline mutations in the CBL tumor-suppressor gene cause a Noonan syndrome-like phenotype.Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation.Effects of partner proteins on BCA2 RING ligase activity.Molecular Mechanisms that Regulate Epidermal Growth Factor Receptor Inactivationc-Cbl-mediated degradation of TRAIL receptors is responsible for the development of the early phase of TRAIL resistance.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.GAPex-5 mediates ubiquitination, trafficking, and degradation of epidermal growth factor receptor.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Endocytosis and intracellular trafficking of ErbBs.Role of c-Cbl carboxyl terminus in serotonin 5-HT2A receptor recycling and resensitization.
P2860
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P2860
Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Cbl-mediated ubiquitinylation ...... s dispensable for endocytosis.
@en
type
label
Cbl-mediated ubiquitinylation ...... s dispensable for endocytosis.
@en
prefLabel
Cbl-mediated ubiquitinylation ...... s dispensable for endocytosis.
@en
P2093
P2860
P356
P1476
Cbl-mediated ubiquitinylation ...... s dispensable for endocytosis.
@en
P2093
Alagarsamy L Reddi
Amiya Ghosh
Biswanath Majumder
David Bowtell
Hamid Band
Ingrid L Dodge
Karen Mullane-Robinson
Manjari Dimri
P2860
P304
28950-28960
P356
10.1074/JBC.M304474200
P407
P577
2003-05-18T00:00:00Z