Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements.
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Long-Range Regulation of V(D)J RecombinationB cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5Transcriptional repressor Gfi1 integrates cytokine-receptor signals controlling B-cell differentiation.Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.The yin and yang of chromatin spatial organization.A novel functional rabbit IL-7 isoform.c-Cbl deficiency leads to diminished lymphocyte development and functions in an age-dependent manner.A stepwise epigenetic process controls immunoglobulin allelic exclusion.Gene segment selection in V(D)J recombination: accessibility and beyond.Seeing is believing: illuminating the source of in vivo interleukin-7.Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus.B-cell homeostasis: digital survival or analog growth?Many levels of control of V gene rearrangement frequency.How to keep V(D)J recombination under control.Regulation of immunoglobulin heavy-chain gene rearrangements.Selective gene expression in multigene families from yeast to mammals.Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations.Interleukin-7 receptor alpha (IL-7Ralpha) deficiency: cellular and molecular bases. Analysis of clinical, immunological, and molecular features in 16 novel patients.Potential roles for short RNAs in lymphocytes.Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci.Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.Turning T-cell receptor beta recombination on and off: more questions than answers.IL-7 receptor signaling is necessary for stage transition in adult B cell development through up-regulation of EBF.Functional analysis of histone methyltransferase g9a in B and T lymphocytes.Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctionsA plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.Temporal and spatial regulation of V(D)J recombination: interactions of extrinsic factors with the RAG complex.Epigenetic regulation of V(D)J recombination.Regulation of antigen receptor gene assembly by genetic-epigenetic crosstalk.IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time.Interleukin 7 and thymic stromal lymphopoietin: from immunity to leukemia.Mechanisms of pre-B-cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia.Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.Targeted inhibition of V(D)J recombination by a histone methyltransferase.Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.Control of V(D)J Recombination through Transcriptional Elongation and Changes in Locus Chromatin Structure and Nuclear Organization.IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle.HMGA1 co-activates transcription in B cells through indirect association with DNA.Tobacco habituated and non-habituated subjects exhibit different mutational spectrums in head and neck squamous cell carcinoma.
P2860
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P2860
Transient IL-7/IL-7R signaling provides a mechanism for feedback inhibition of immunoglobulin heavy chain gene rearrangements.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Transient IL-7/IL-7R signaling ...... avy chain gene rearrangements.
@en
type
label
Transient IL-7/IL-7R signaling ...... avy chain gene rearrangements.
@en
prefLabel
Transient IL-7/IL-7R signaling ...... avy chain gene rearrangements.
@en
P1433
P1476
Transient IL-7/IL-7R signaling ...... avy chain gene rearrangements.
@en
P2093
Dipanjan Chowdhury
Ranjan Sen
P304
P356
10.1016/S1074-7613(03)00030-X
P407
P577
2003-02-01T00:00:00Z