Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.

Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.

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http://www.wikidata.org/entity/Q40685818
From animal models to human disease: a genetic approach for personalized medicine in ALSAmyotrophic lateral sclerosis patient iPSC-derived astrocytes impair autophagy via non-cell autonomous mechanisms.Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects.Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesisA Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by RapamycinStress granules at the intersection of autophagy and ALS.Autophagy Dysregulation in ALS: When Protein Aggregates Get Out of Hand.Ageing as a risk factor for ALS/FTD.Autophagy as a common pathway in amyotrophic lateral sclerosis.Rapamycin treatment for amyotrophic lateral sclerosis: Protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial).
P2860

Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.

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http://www.wikidata.org/entity/Q40685818
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
@en
type
label
Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
@en
prefLabel
Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P921
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P1433
P1476
Rapamycin alleviates pathogenesis of a new Drosophila model of ALS-TDP.
@en
P2093
P2860
P304
P31
P356
10.3109/01677063.2015.1077832
P433
P478
P577
P698
P921