Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies.
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Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesTargeting the redox balance in inflammatory skin conditionsSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysIron(III)-salophene: an organometallic compound with selective cytotoxic and anti-proliferative properties in platinum-resistant ovarian cancer cellsTreatment with the reactive oxygen species scavenger EUK-207 reduces lung damage and increases survival during 1918 influenza virus infection in miceSynthesis, characterization, and reactivity studies of a water-soluble bis(alkoxo)(carboxylato)-bridged diMn(III) complex modeling the active site in catalase.Cardiovascular disease could be contained based on currently available data!Metal complexes as potential modulators of inflammatory and autoimmune responses.Prevention of cognitive deficits and brain oxidative stress with superoxide dismutase/catalase mimetics in aged mice.Targeting the Renin-angiotensin system combined with an antioxidant is highly effective in mitigating radiation-induced lung damage.Catalytic antioxidants and neurodegenerationSuperoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialPotential therapeutic benefits of strategies directed to mitochondria.Stability, disposition, and penetration of catalytic antioxidants Mn-porphyrin and Mn-salen and of methylprednisolone in spinal cord injury.Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics.Emerging themes in manganese transport, biochemistry and pathogenesis in bacteria.Experimental antioxidant therapy in ataxia telangiectasia.Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation.Striatal neuroprotection from neonatal hypoxia-ischemia in piglets by antioxidant treatment with EUK-134 or edaravone.Can ageing be slowed?: Hormetic and redox perspectives.A role for apoptosis-inducing factor in T cell development.A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin.The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum.Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways.Catalase and glutathione peroxidase mimics.Salen Mn complexes mitigate radiation injury in normal tissues.Texaphyrins: tumor localizing redox active expanded porphyrinsTherapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia.Radioprotection of normal tissue cells.Superoxide dismutase/catalase mimetics but not MAP kinase inhibitors are neuroprotective against oxygen/glucose deprivation-induced neuronal death in hippocampus.Copper signaling axis as a target for prostate cancer therapeutics.Syntheses and structure-activity relationships of seven manganese-salen derivatives as anti-amyloidogenic and fibril-destabilizing agents against hen egg-white lysozyme aggregation.Evaluation of the anti-oxidant properties of a SOD-mimic Mn-complex in activated macrophages.Structure-activity relationship of 15 different Mn-salen derivatives against free radicals.Eliminating Nox2 reactive oxygen species production protects dystrophic skeletal muscle from pathological calcium influx assessed in vivo by manganese-enhanced magnetic resonance imaging.Effects of metal salophene and saldach complexes on lymphoma and leukemia cells.Fe(III)-salen and salphen complexes induce caspase activation and apoptosis in human cells.Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide.Only one of a wide assortment of manganese-containing SOD mimicking compounds rescues the slow aerobic growth phenotypes of both Escherichia coli and Saccharomyces cerevisiae strains lacking superoxide dismutase enzymes.
P2860
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P2860
Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Salen-manganese complexes as c ...... activity relationship studies.
@en
type
label
Salen-manganese complexes as c ...... activity relationship studies.
@en
prefLabel
Salen-manganese complexes as c ...... activity relationship studies.
@en
P2093
P356
P1476
Salen-manganese complexes as c ...... activity relationship studies.
@en
P2093
Bernard Malfroy
Catherine Bucay Marcus
Christy A Adinolfi
Evelyne Malfroy
Georges Tocco
Henry Kruk
Julius Mascarenhas
Karl Huffman
Keith Baker
Natalie Lazarowych
P304
P356
10.1021/JM020207Y
P407
P577
2002-09-01T00:00:00Z