A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
about
Local amplification of glucocorticoids in the aging brain and impaired spatial memoryRepression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP betaRecruitment of octamer transcription factors to DNA by glucocorticoid receptor.Cross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain bindingA nuclear isoform of the focal adhesion LIM-domain protein Trip6 integrates activating and repressing signals at AP-1- and NF-kappaB-regulated promotersDissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effectsDNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expressionGlucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3A nuclear action of the eukaryotic cochaperone RAP46 in downregulation of glucocorticoid receptor activityGlucocorticoid receptor-dependent gene regulatory networks.Specificity and sensitivity of glucocorticoid signaling in health and diseaseDNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and ActivityThe structural basis of direct glucocorticoid-mediated transrepressionStructures and mechanism for the design of highly potent glucocorticoidsGlucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanismGlucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1Induction of the E-selectin promoter by interleukin 1 and tumour necrosis factor alpha, and inhibition by glucocorticoidsCompound A, a dissociated glucocorticoid receptor modulator, inhibits T-bet (Th1) and induces GATA-3 (Th2) activity in immune cellsRegulation of the rat UGT1A6 by glucocorticoids involves a cryptic glucocorticoid response elementSteroid receptor heterodimerization demonstrated in vitro and in vivoDissection of glucocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis by gene targeting in mice.Stress levels of glucocorticoids inhibit LHβ-subunit gene expression in gonadotrope cells.Memory modulation.Hypothalamic-pituitary-adrenal axis dysregulation and behavioral analysis of mouse mutants with altered glucocorticoid or mineralocorticoid receptor functionGlucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution.A Quantitative Study of Internal and External Interactions of Homodimeric Glucocorticoid Receptor Using Fluorescence Cross-Correlation Spectroscopy in a Live Cell.Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.The human glucocorticoid receptor: molecular basis of biologic functionCrosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesMinireview: latest perspectives on antiinflammatory actions of glucocorticoids.Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor.Insights on glucocorticoid receptor activity modulation through the binding of rigid steroids.A theoretical framework for gene induction and experimental comparisons.Molecular mechanisms of glucocorticoid action: what is important?Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory.Distinct glucocorticoid receptor transcriptional regulatory surfaces mediate the cytotoxic and cytostatic effects of glucocorticoidsNovel mechanism of steroid action in skin through glucocorticoid receptor monomers.Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line
P2860
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P2860
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
A distinct modulating domain i ...... the transcription factor AP-1.
@en
type
label
A distinct modulating domain i ...... the transcription factor AP-1.
@en
prefLabel
A distinct modulating domain i ...... the transcription factor AP-1.
@en
P2093
P2860
P1433
P1476
A distinct modulating domain i ...... the transcription factor AP-1.
@en
P2093
Herrlich P
Kullmann M
Rahmsdorf HJ
P2860
P304
P407
P577
1994-09-01T00:00:00Z