TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes.
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Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosisPhosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signallingA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathLigand bound beta1 integrins inhibit procaspase-8 for mediating cell adhesion-mediated drug and radiation resistance in human leukemia cellsBiological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agentExtracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase-1 expression and activityAn autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival.Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behaviorIntracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphateAcid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppressionCaveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line.Signaling by IL-12 and IL-23 and the immunoregulatory roles of STAT4.An assay system for measuring the acute production of sphingosine 1-phosphate in intact monolayers.Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein ExpressionLiver acid sphingomyelinase inhibits growth of metastatic colon cancer.Mitochondrial glutathione: hepatocellular survival-death switch.PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomyA critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability.Lipopolysaccharide and Tumor Necrosis Factor Alpha Inhibit Interferon Signaling in Hepatocytes by Increasing Ubiquitin-Like Protease 18 (USP18) Expression.Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase.Differential regulation of sphingosine kinases 1 and 2 in lung injury.Sphingosine kinase 1 regulates tumor necrosis factor-mediated RANTES induction through p38 mitogen-activated protein kinase but independently of nuclear factor κB activation.C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.Sphingolipidomics: methods for the comprehensive analysis of sphingolipids.Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance.Local effects of the sphingosine 1-phosphate on prostaglandin F2alpha-induced luteolysis in the pregnant ratImplication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family MoleculesAdiponectin ameliorates doxorubicin-induced cardiotoxicity through Akt protein-dependent mechanismTumor necrosis factor alpha-induced interleukin-8 production via NF-kappaB and phosphatidylinositol 3-kinase/Akt pathways inhibits cell apoptosis in human hepatocytes.Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.S-adenosylhomocysteine inhibits NF-κB-mediated gene expression in hepatocytes and confers sensitivity to TNF cytotoxicity.Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression.Prostaglandin E2 downregulates TNF-alpha-induced production of matrix metalloproteinase-1 in HCS-2/8 chondrocytes by inhibiting Raf-1/MEK/ERK cascade through EP4 prostanoid receptor activation.Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells.Inhibition of NF-kappaB renders human juvenile costal chondrocyte cell lines sensitive to TNF-alpha-mediated cell death.Phospholipase Cϵ Activates Nuclear Factor-κB Signaling by Causing Cytoplasmic Localization of Ribosomal S6 Kinase and Facilitating Its Phosphorylation of Inhibitor κB in Colon Epithelial Cells.Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells.Apoptosis induction by OTA and TNF-α in cultured primary rat hepatocytes and prevention by silibinin.Involvement of sphingosine kinase in TNF-alpha-stimulated tetrahydrobiopterin biosynthesis in C6 glioma cells.
P2860
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P2860
TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
TNF-alpha-induced sphingosine ...... pathway in human hepatocytes.
@en
type
label
TNF-alpha-induced sphingosine ...... pathway in human hepatocytes.
@en
prefLabel
TNF-alpha-induced sphingosine ...... pathway in human hepatocytes.
@en
P2093
P1476
TNF-alpha-induced sphingosine ...... pathway in human hepatocytes.
@en
P2093
D A Brenner
H Moriwaki
S Nakashima
P304
P356
10.4049/JIMMUNOL.167.1.173
P407
P577
2001-07-01T00:00:00Z