A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

Item
http://www.wikidata.org/entity/Q40798838
Up-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-ADThe influence of long-term treatment with psychotropic drugs on cytochrome P450: the involvement of different mechanisms.The brain dopaminergic system as an important center regulating liver cytochrome P450 in the rat.A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3.Cell-based systems to assess nuclear receptor activation and their use in drug development.Receptor-dependent transcriptional activation of cytochrome P4503A genes: induction mechanisms, species differences and interindividual variation in man.Gadd45β is an inducible coactivator of transcription that facilitates rapid liver growth in miceTransactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites.Synthetic drugs and natural products as modulators of constitutive androstane receptor (CAR) and pregnane X receptor (PXR).PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor.A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway.Dual action of oestrogens on the mouse constitutive androstane receptor.Characterization of ligand-dependent activation of bovine and pig constitutive androstane (CAR) and pregnane X receptors (PXR) with interspecies comparisons.In vivo and mechanistic evidence of nuclear receptor CAR induction by artemisinin.Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans.
P2860

A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

Item
http://www.wikidata.org/entity/Q40798838
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
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2001年學術文章
@zh-hant
name
A novel drug-regulated gene ex ...... ive androstane receptor (CAR).
@en
type
label
A novel drug-regulated gene ex ...... ive androstane receptor (CAR).
@en
prefLabel
A novel drug-regulated gene ex ...... ive androstane receptor (CAR).
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
A novel drug-regulated gene ex ...... tive androstane receptor (CAR)
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P698