Reengineering granulocyte colony-stimulating factor for enhanced stability.
about
Combinatorial approaches to protein stability and structure.Ubiquitin fusion expression and tissue-dependent targeting of hG-CSF in transgenic tobacco.Antiapoptotic effects of Phe140Asn, a novel human granulocyte colony-stimulating factor mutant in H9c2 rat cardiomyocytesImproved drug-like properties of therapeutic proteins by directed evolution.The unique cysteine knot regulates the pleotropic hormone leptin.Pierced Lasso Bundles are a new class of knot-like motifspH responsive granulocyte colony-stimulating factor variants with implications for treating Alzheimer's disease and other central nervous system disorders.Cytokine refacing effect reduces granulocyte macrophage colony-stimulating factor susceptibility to antibody neutralization.Aggregation of granulocyte-colony stimulating factor in vitro involves a conformationally altered monomeric state.Development of a cytokine analog with enhanced stability using computational ultrahigh throughput screeningMonitoring Effects of Excipients, Formulation Parameters and Mutations on the High Order Structure of Filgrastim by NMR.Optimizing protein stability in vivoModulation of protein aggregation by polyethylene glycol conjugation: GCSF as a case study.pH Dependence of structural stability of interleukin-2 and granulocyte colony-stimulating factor.Enthalpic and entropic contributions mediate the role of disulfide bonds on the conformational stability of interleukin-4.Mass spectrometric distinction of in-source and in-solution pyroglutamate and succinimide in proteins: a case study on rhG-CSF.Optimization of auto-induction medium for G-CSF production by Escherichia coli using artificial neural networks coupled with genetic algorithm.Expression of recombinant human mutant granulocyte colony stimulating factor (Nartograstim) in Escherichia coli.
P2860
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P2860
Reengineering granulocyte colony-stimulating factor for enhanced stability.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Reengineering granulocyte colony-stimulating factor for enhanced stability.
@en
type
label
Reengineering granulocyte colony-stimulating factor for enhanced stability.
@en
prefLabel
Reengineering granulocyte colony-stimulating factor for enhanced stability.
@en
P2093
P2860
P356
P1476
Reengineering granulocyte colony-stimulating factor for enhanced stability.
@en
P2093
P2860
P304
33465-33470
P356
10.1074/JBC.M104494200
P407
P577
2001-06-13T00:00:00Z