In vitro methods for assessing human hepatic drug metabolism: their use in drug development.
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CYP2C9 protein interactions with cytochrome b(5): effects on the coupling of catalysisEvaluation of 7-benzyloxy-4-trifluoromethylcoumarin, some other 7-hydroxy-4-trifluoromethylcoumarin derivatives and 7-benzyloxyquinoline as fluorescent substrates for rat hepatic cytochrome P450 enzymesSummary of information on human CYP enzymes: human P450 metabolism data.The role of CYP2B6 in human xenobiotic metabolism.The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomesHuman cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors.In vitro cytochrome P450-mediated hepatic activities for five substrates in specific pathogen free chickens.Fish models for environmental carcinogenesis: the rainbow trout.The inhibition of CYP enzymes in mouse and human liver by pilocarpineCytochrome P450 enzyme mediated herbal drug interactions (Part 1)Cytochrome P450 enzyme mediated herbal drug interactions (Part 2)Study of drug metabolism by xanthine oxidase.New technologies and screening strategies for hepatotoxicity: use of in vitro models.Expression of CYP4F2 in human liver and kidney: assessment using targeted peptide antibodies.Engineering a perfusable 3D human liver platform from iPS cells.The use of in vitro metabolism techniques in the planning and interpretation of drug safety studies.The role of CYP enzymes in cocaine-induced liver damage.Stereoselectivity in S- and N-oxygenation by the mammalian flavin-containing and cytochrome P-450 monooxygenases.Past, present, and future applications of precision-cut liver slices for in vitro xenobiotic metabolism.Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.The human drug metabolizing cytochromes P450.CYP3A4 drug interactions: correlation of 10 in vitro probe substrates.Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactionsDifferential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes.Dog liver microsomal P450 enzyme-mediated toluene biotransformation.Metabolism of a novel phosphodiesterase-IV inhibitor (V11294) by human hepatic cytochrome P450 forms.4-Biphenylaldehyde and 9-anthraldehyde: two fluorescent substrates for determining P450 enzyme activities in rat and human.Interlaboratory comparison of the assessment of P450 activities in human hepatic microsomal samples.Metabolism of Zaleplon by human hepatic microsomal cytochrome P450 isoforms.Phase I metabolism of ganstigmine. Rat, dog, monkey and human liver microsomal extracts investigated by liquid chromatography electrospray tandem mass spectrometry.
P2860
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P2860
In vitro methods for assessing human hepatic drug metabolism: their use in drug development.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
In vitro methods for assessing ...... their use in drug development.
@en
type
label
In vitro methods for assessing ...... their use in drug development.
@en
prefLabel
In vitro methods for assessing ...... their use in drug development.
@en
P2093
P2860
P1476
In vitro methods for assessing ...... their use in drug development.
@en
P2093
Cashman JR
Shipley LA
Stevens JC
Vandenbranden M
Wrighton SA
P2860
P304
P356
10.3109/03602539308993982
P407
P577
1993-01-01T00:00:00Z