about
Molecular cloning, genomic characterization and over-expression of a novel gene, XRRA1, identified from human colorectal cancer cell HCT116Clone2_XRR and macaque testisXRCC3 promotes homology-directed repair of DNA damage in mammalian cellsEndogenous DNA double-strand breaks: production, fidelity of repair, and induction of cancerMaking ends meet: repairing breaks in bacterial DNA by non-homologous end-joiningAutophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair.Importance of Polη for damage-induced cohesion reveals differential regulation of cohesion establishment at the break site and genome-wideDietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cellsGenetic steps of mammalian homologous repair with distinct mutagenic consequencesDownregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factorKu DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cellsPathways of DNA double-strand break repair during the mammalian cell cycleNuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damageRAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair.DNA-Dependent protein kinase is not required for efficient lentivirus integrationDNA double-strand break repair and the evolution of intron density.Analysis of variable (diversity) joining recombination in DNAdependent protein kinase (DNA-PK)-deficient mice reveals DNA-PK-independent pathways for both signal and coding joint formation.Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting proteinBoth V(D)J recombination and radioresistance require DNA-PK kinase activity, though minimal levels suffice for V(D)J recombination.Reverse genetic studies of homologous DNA recombination using the chicken B-lymphocyte line, DT40.An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria.Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs)Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence of histone H1.Successful targeting and disruption of an integrated reporter lentivirus using the engineered homing endonuclease Y2 I-AniI.Stimulation of homologous recombination through targeted cleavage by chimeric nucleases.The over-expression of the β2 catalytic subunit of the proteasome decreases homologous recombination and impairs DNA double-strand break repair in human cells.MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repairT7 single strand DNA binding protein but not T7 helicase is required for DNA double strand break repair.RAD50 function is essential for telomere maintenance in Arabidopsis.The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies.A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.Efficient gene targeting in Drosophila with zinc-finger nucleasesDNA damage-inducible and RAD52-independent repair of DNA double-strand breaks in Saccharomyces cerevisiae.Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleasesThe homologous chromosome is an effective template for the repair of mitotic DNA double-strand breaks in Drosophila.The brown algae Pl.LSU/2 group II intron-encoded protein has functional reverse transcriptase and maturase activities.The role of BRCA1 in DNA damage response.Impact of DNA ligase IV on the fidelity of end joining in human cells.Homologous and non-homologous recombination differentially affect DNA damage repair in mice.Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy.Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
DNA breakage and repair.
@en
type
label
DNA breakage and repair.
@en
prefLabel
DNA breakage and repair.
@en
P1433
P1476
DNA breakage and repair.
@en
P2093
P304
P577
1998-01-01T00:00:00Z