Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.
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Effect of oral administration of emtricitabine on woodchuck hepatitis virus replication in chronically infected woodchucksAntiviral L-nucleosides specific for hepatitis B virus infectionAntiviral activity of beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine in woodchucks chronically infected with woodchuck hepatitis virusIn vivo assessment of mitochondrial toxicity of metacavir in Rhesus monkeys after three months of intravenous administration.Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis BPharmacodynamics of (-)-beta-2',3'-dideoxy-3'-thiacytidine in chronically virus-infected woodchucks compared to its pharmacodynamics in humans.The woodchuck as an animal model for pathogenesis and therapy of chronic hepatitis B virus infectionAntiviral effect of oral administration of tenofovir disoproxil fumarate in woodchucks with chronic woodchuck hepatitis virus infection.Pharmacology and pharmacokinetics of the antiviral agent beta-D-2',3'-dideoxy-3'-oxa-5-fluorocytidine in cells and rhesus monkeysAntiviral activities of oral 1-O-hexadecylpropanediol-3-phosphoacyclovir and acyclovir in woodchucks with chronic woodchuck hepatitis virus infectionAntiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucksClevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks.Aging and HIV/AIDS: pathogenetic role of therapeutic side effectsMitochondrial dna depletion, oxidative stress, and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors.The woodchuck model of hepatitis B virus infection.Anti-HBV specific beta-L-2'-deoxynucleosides.Evaluation of mitochondrial toxicity in Marmota himalayana treated with metacavir, a novel 2',3'-dideoxyguanosine prodrug for treatment of hepatitis B Virus.Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.Do preclinical testing strategies help predict human hepatotoxic potentials?Antiviral effect of orally administered (-)-beta-D-2-aminopurine dioxolane in woodchucks with chronic woodchuck hepatitis virus infection.Inhibition of hepatitis B virus by a novel L-nucleoside, beta-L-D4A and related analogues.Targets of emerging therapies for viral hepatitis B and C.Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection.Correlation of virus and host response markers with circulating immune complexes during acute and chronic woodchuck hepatitis virus infection.Mitochondrial DNA impairment in nucleoside reverse transcriptase inhibitor-associated cardiomyopathyMetabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective.Animal models of idiosyncratic drug-induced liver injury--current status.Experimental models and therapeutic approaches for HBV.Regulatory Forum Opinion Piece*: Use and Utility of Animal Models of Disease for Nonclinical Safety Assessment: A Pharmaceutical Industry Survey.Current challenges and controversies in drug-induced liver injury.Efficacy of the carbocyclic 2'-deoxyguanosine nucleoside BMS-200475 in the woodchuck model of hepatitis B virus infection.Viral pharmacodynamic model for (-)-beta-2',3'-dideoxy-5-fluoro-3'-thiacytidine (emtricitabine) in chronically infected woodchucks.Entecavir for treatment of hepatitis B virus displays no in vitro mitochondrial toxicity or DNA polymerase gamma inhibition.Profound antiviral effect of oral administration of MIV-210 on chronic hepadnaviral infection in a woodchuck model of hepatitis BNonalcoholic fatty liver disease and hepatic cirrhosis: Comparison with viral hepatitis-associated steatosis.Small-molecule effectors of hepatitis B virus capsid assembly give insight into virus life cycle.An evaluation of the toxicities of 2'-fluorouridine and 2'-fluorocytidine-HCl in F344 rats and woodchucks (Marmota monax).
P2860
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P2860
Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Antiviral activity and toxicit ...... f hepatitis B virus infection.
@en
type
label
Antiviral activity and toxicit ...... f hepatitis B virus infection.
@en
prefLabel
Antiviral activity and toxicit ...... f hepatitis B virus infection.
@en
P2093
P356
P1433
P1476
Antiviral activity and toxicit ...... f hepatitis B virus infection.
@en
P2093
Ascenzi MA
Baldwin BH
Bowsher RR
Colacino JM
Engelhardt JA
Hornbuckle WE
P304
P356
10.1002/HEP.510280124
P407
P577
1998-07-01T00:00:00Z