Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.

Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.

Item
http://www.wikidata.org/entity/Q40852695
Mutant p53: one name, many proteins.Transcription regulation by mutant p53.Induction of genetic instability by gain-of-function p53 cancer mutants.The consequence of oncomorphic TP53 mutations in ovarian cancer.New insights into p53 signaling and cancer cell response to DNA damage: implications for cancer therapy.RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response.Mutant p53 in cancer: new functions and therapeutic opportunities.Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53.DNA substrate dependence of p53-mediated regulation of double-strand break repair.Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes.Hetero-oligomerization does not compromise 'gain of function' of tumor-derived p53 mutants.
P2860

Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.

Item
http://www.wikidata.org/entity/Q40852695
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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2000年论文
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2000年论文
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name
Tumor-derived p53 mutant C174Y ...... and enhances colony formation.
@en
type
label
Tumor-derived p53 mutant C174Y ...... and enhances colony formation.
@en
prefLabel
Tumor-derived p53 mutant C174Y ...... and enhances colony formation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Tumor-derived p53 mutant C174Y ...... and enhances colony formation.
@en
P2093
P2860
P304
P31
P356
10.1002/1097-0215(20001015)88:2<162::AID-IJC3>3.0.CO;2-M
P433
P478
P577
P698