Lysosomal neuraminidase. Catalytic activation in insect cells is controlled by the protective protein/cathepsin A.
about
Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2Proteolytic Activation of Human Cathepsin ALysosomal sialidase (neuraminidase-1) is targeted to the cell surface in a multiprotein complex that facilitates elastic fiber assemblyOverexpression of cytosolic sialidase Neu2 induces myoblast differentiation in C2C12 cellsNEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signalingHuman airway epithelia express catalytically active NEU3 sialidaseLysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-β secretion via deregulated lysosomal exocytosisVacuolization and alterations of lysosomal membrane proteins in cochlear marginal cells contribute to hearing loss in neuraminidase 1-deficient miceLysosomal multienzyme complex: pros and cons of working togetherCharacterization of cysteine protease-like genes in the striped rice stem borer, Chilo suppressalis.NEU1 and NEU3 sialidase activity expressed in human lung microvascular endothelia: NEU1 restrains endothelial cell migration, whereas NEU3 does notPathogenesis, Emerging therapeutic targets and Treatment in Sialidosis.Neuraminidase-1 is required for the normal assembly of elastic fibersChaperone-mediated gene therapy with recombinant AAV-PPCA in a new mouse model of type I sialidosisHeterodimerization of the sialidase NEU1 with the chaperone protective protein/cathepsin A prevents its premature oligomerization.NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia.New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability.Enzyme replacement for GM1-gangliosidosis: Uptake, lysosomal activation, and cellular disease correction using a novel β-galactosidase:RTB lectin fusion.Cytosolic sialidase Neu2 upregulation during PC12 cells differentiation.Protective protein/cathepsin A rescues N-glycosylation defects in neuraminidase-1.Tumor necrosis factor-alpha induces functionally active hyaluronan-adhesive CD44 by activating sialidase through p38 mitogen-activated protein kinase in lipopolysaccharide-stimulated human monocytic cells.
P2860
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P2860
Lysosomal neuraminidase. Catalytic activation in insect cells is controlled by the protective protein/cathepsin A.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Lysosomal neuraminidase. Catal ...... rotective protein/cathepsin A.
@en
type
label
Lysosomal neuraminidase. Catal ...... rotective protein/cathepsin A.
@en
prefLabel
Lysosomal neuraminidase. Catal ...... rotective protein/cathepsin A.
@en
P2860
P356
P1476
Lysosomal neuraminidase. Catal ...... rotective protein/cathepsin A.
@en
P2093
P2860
P304
37657-37663
P356
10.1074/JBC.M007380200
P407
P577
2000-12-01T00:00:00Z