Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice. - Wikidata - wikimedia - TriplyDB

Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice.

Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice.

http://www.wikidata.org/entity/Q40860354

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Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury The role of necroptosis in neurosurgical diseases Role of Akt-independent mTORC1 and GSK3β signaling in sublethal NMDA-induced injury and the recovery of neuronal electrophysiology and survival Role of Akt and mammalian target of rapamycin in functional outcome after concussive brain injury in mice Genetic activation of mTORC1 signaling worsens neurocognitive outcome after traumatic brain injury.Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation Beneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury.Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain.Neuroprotective levels of IGF-1 exacerbate epileptogenesis after brain injury.mTOR Inhibition: From Aging to Autism and Beyond.Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy.A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials.Hydrogen sulfide offers neuroprotection on traumatic brain injury in parallel with reduced apoptosis and autophagy in mice.Akt and mTOR mediate programmed necrosis in neurons.mTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis.mTOR inhibitors as a new therapeutic option for epilepsy.mTOR in Brain Physiology and Pathologies.Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII).Traumatic Brain Injury Stimulates Neural Stem Cell Proliferation via Mammalian Target of Rapamycin Signaling Pathway Activation.Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression.Upregulation of 3-MST Relates to Neuronal Autophagy After Traumatic Brain Injury in Mice.TIMP3 Attenuates the Loss of Neural Stem Cells, Mature Neurons and Neurocognitive Dysfunction in Traumatic Brain Injury.Poloxamer 188 Attenuates Cerebral Hypoxia/Ischemia Injury in Parallel with Preventing Mitochondrial Membrane Permeabilization and Autophagic Activation.Phenotypic conversions of "protoplasmic" to "reactive" astrocytes in Alexander disease.The mTOR pathway is activated in glial cells in mesial temporal sclerosis.Converging early responses to brain injury pave the road to epileptogenesis.Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift.Erythropoietin attenuates motor neuron programmed cell death in a burn animal model.Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update.Lysosomal damage after spinal cord injury causes accumulation of RIPK1 and RIPK3 proteins and potentiation of necroptosis.Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo - in search of potential anti-epileptogenic strategies for temporal lobe epilepsy

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P2860

Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice.

http://www.wikidata.org/entity/Q40860354

description

2011 nî lūn-bûn

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2011年論文

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2011年论文

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2011年论文

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name

Combination therapy targeting ...... olled cortical impact in mice.

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Combination therapy targeting ...... olled cortical impact in mice.

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Combination therapy targeting ...... olled cortical impact in mice.

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Journal of Cerebral Blood Flow & Metabolism

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Combination therapy targeting ...... olled cortical impact in mice.

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P2093

Eng H Lo

http://www.w3.org/2001/XMLSchema#string

Jianhua Qiu

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Jimmy Zhang

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Juyeon Park

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Michael J Whalen

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Xiaoxia Zhu

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P2860

Negative regulation of the serine/threonine kinase B-Raf by Akt

Activation of mammalian target of rapamycin signaling in spatial learning

Alterations in mammalian target of rapamycin signaling pathways after traumatic brain injury

Acute plasmalemma permeability and protracted clearance of injured cells after controlled cortical impact in mice.

Central exercise action increases the AMPK and mTOR response to leptin

GSK3 takes centre stage more than 20 years after its discovery.

Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats.

AKT inhibition relieves feedback suppression of receptor tyrosine kinase expression and activity

Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergy.

Protein kinase signaling cascades in CNS trauma.

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330-340

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10.1038/JCBFM.2011.131

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2

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32

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Alexei Degterev

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