The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
about
Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3Induction of colonic epithelial cell apoptosis by p47-dependent oxidantsFoxM1, a critical regulator of oxidative stress during oncogenesisUp-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaksMUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated MechanismRedox-directed cancer therapeutics: molecular mechanisms and opportunitiesNovel redox-dependent regulation of NOX5 by the tyrosine kinase c-AblA new view of carcinogenesis and an alternative approach to cancer therapyThe role of RecQ helicases in non-homologous end-joiningReactive oxygen species in cancer stem cellsDepolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROSOxidative stress responses and NRF2 in human leukaemiaDisease progression mediated by egr-1 associated signaling in response to oxidative stressEffective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanismBCR/ABL induces chromosomal instability after genotoxic stress and alters the cell death thresholdA novel AHI-1-BCR-ABL-DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy.Novel role of NADPH oxidase in angiogenesis and stem/progenitor cell function.Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway.Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies.Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells.BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells.NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.Selenium suppresses leukemia through the action of endogenous eicosanoids.Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms.Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene.Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.Targeting abnormal DNA double-strand break repair in tyrosine kinase inhibitor-resistant chronic myeloid leukemias.Signalling apoptosis: a radical approach.Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice.The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantationBCR/ABL regulates response to DNA damage: the role in resistance to genotoxic treatment and in genomic instability.Regulatory effects of sestrin 3 (SESN3) in BCR-ABL expressing cellsIdentification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia.Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome"The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activityARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells.Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias.
P2860
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P2860
The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
The BCR/ABL tyrosine kinase in ...... pecies in hematopoietic cells.
@en
type
label
The BCR/ABL tyrosine kinase in ...... pecies in hematopoietic cells.
@en
prefLabel
The BCR/ABL tyrosine kinase in ...... pecies in hematopoietic cells.
@en
P2093
P2860
P356
P1476
The BCR/ABL tyrosine kinase in ...... pecies in hematopoietic cells.
@en
P2093
Greenfield EA
Griffin JD
Shrikhande G
P2860
P304
24273-24278
P356
10.1074/JBC.M002094200
P407
P577
2000-08-01T00:00:00Z