Direct binding and activation of STAT transcription factors by the herpesvirus saimiri protein tip.
about
Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifsTyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cellsCirculating Th17, Th22, and Th1 cells are increased in psoriasisHerpesvirus ateles Tio can replace herpesvirus saimiri StpC and Tip oncoproteins in growth transformation of monkey and human T cellsDownregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural hostAssociation of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor.Activation of the STAT6 transcription factor in Jurkat T-cells by the herpesvirus saimiri Tip protein.NFkappaB signaling is induced by the oncoprotein Tio through direct interaction with TRAF6.Molecular mechanisms of the effect of herpesvirus saimiri protein StpC on the signaling pathway leading to NF-kappaB activation.Inhibition of T cell receptor signal transduction by tyrosine kinase-interacting protein of Herpesvirus saimiri.Actin-dependent activation of serum response factor in T cells by the viral oncoprotein tip.T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation.Herpesvirus saimiri replaces ZAP-70 for CD3- and CD2-mediated T cell activation.Autocrine stimulation of rhadinovirus-transformed T cells by the chemokine CCL1/I-309.
P2860
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P2860
Direct binding and activation of STAT transcription factors by the herpesvirus saimiri protein tip.
description
2000 nî lūn-bûn
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2000年学术文章
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name
Direct binding and activation ...... rpesvirus saimiri protein tip.
@en
type
label
Direct binding and activation ...... rpesvirus saimiri protein tip.
@en
prefLabel
Direct binding and activation ...... rpesvirus saimiri protein tip.
@en
P2860
P356
P1476
Direct binding and activation ...... rpesvirus saimiri protein tip.
@en
P2093
P2860
P304
16925-16932
P356
10.1074/JBC.M000709200
P407
P577
2000-06-01T00:00:00Z