Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak.
about
Lysosomal storage diseases and the heat shock response: convergences and therapeutic opportunitiesHsp70.1 and related lysosomal factors for necrotic neuronal deathThe lysosome: from waste bag to potential therapeutic targetSphingosine-induced apoptosis is dependent on lysosomal proteasesApoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal ruptureMechanisms of divalent metal toxicity in affective disordersNanoelectrodes for determination of reactive oxygen and nitrogen species inside murine macrophagesInduction of lysosomal membrane permeabilization by compounds that activate p53-independent apoptosis.Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanismsResistance to tumor necrosis factor-induced cell death mediated by PMCA4 deficiency.Lysosomal destabilization in p53-induced apoptosisLysosomal involvement in apoptosis.Susceptibility of lysosomes to rupture is a determinant for plasma membrane disruption in tumor necrosis factor alpha-induced cell death.The human brm protein is cleaved during apoptosis: the role of cathepsin GBrevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathwayDestination 'lysosome': a target organelle for tumour cell killing?Procoagulant potential of platelet alpha granules.Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay.Autophagy and neuronal cell death in neurological disordersLysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes.Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation.The Octyl Ester of Ginsenoside Rh2 Induces Lysosomal Membrane Permeabilization via Bax Translocation.Lysosomes in iron metabolism, ageing and apoptosis.Heat shock proteins: essential proteins for apoptosis regulation.Lysosomal serine protease CLN2 regulates tumor necrosis factor-alpha-mediated apoptosis in a Bid-dependent mannerRegulation of apoptosis-associated lysosomal membrane permeabilization.Some aspects of quantum dot toxicity.Plasma membrane calcium pump regulation by metabolic stress.Nanopreparations for organelle-specific delivery in cancerActivation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity.Lysosomal destabilization contributes to apoptosis of germinal center B-lymphocytes.Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity.Metabolic regulation of the PMCA: Role in cell death and survival.Lysosomal membrane permeabilization contributes to elemene emulsion-induced apoptosis in A549 cells.Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent.Caspase- and mitochondrial dysfunction-dependent mechanisms of lysosomal leakage and cathepsin B activation in DNA damage-induced apoptosis.Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity.Streptococcus oralis Induces Lysosomal Impairment of Macrophages via Bacterial Hydrogen PeroxideNovel cellular defenses against iron and oxidation: ferritin and autophagocytosis preserve lysosomal stability in airway epithelium.
P2860
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P2860
Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Oxidative stress, growth facto ...... ptosis through lysosomal leak.
@en
type
label
Oxidative stress, growth facto ...... ptosis through lysosomal leak.
@en
prefLabel
Oxidative stress, growth facto ...... ptosis through lysosomal leak.
@en
P2860
P1433
P1476
Oxidative stress, growth facto ...... ptosis through lysosomal leak.
@en
P2093
P2860
P356
10.1179/135100099101534675
P577
1999-01-01T00:00:00Z