Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity.
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Nanomaterials in humans: identification, characteristics, and potential damageSilica particles cause NADPH oxidase-independent ROS generation and transient phagolysosomal leakageThe phagocytosis and toxicity of amorphous silicaAn overview of caspase: Apoptotic protein for silicosisThe phagocytosis of crystalline silica particles by macrophages.Association Between Occupational Exposures and Sarcoidosis: An Analysis From Death Certificates in the United States, 1988-1999Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicitySilica binding and toxicity in alveolar macrophagesBiocompatibility assessment of Si-based nano- and micro-particlesCellular targets and mechanisms in the cytotoxic action of non-biodegradable engineered nanoparticlesNanomaterials toxicity and cell death modalitiesLipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosisCarbon black and titanium dioxide nanoparticles elicit distinct apoptotic pathways in bronchial epithelial cells.Macrophages phagocytose nonopsonized silica particles using a unique microtubule-dependent pathway.Evaluation of cytotoxic concentration-time response in A549 cells exposed to respirable alpha-quartz.Induction of lysosomal biogenesis in atherosclerotic macrophages can rescue lipid-induced lysosomal dysfunction and downstream sequelaeMulti-parametric analysis of cell death pathways using live-cell microscopy.Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages.Silica-directed mast cell activation is enhanced by scavenger receptorsCysteine cathepsins and caspases in silicosis.Nanotechnology safety concerns revisited.Size-Dependent Mechanism of Intracellular Localization and Cytotoxicity of Mono-Disperse Spherical Mesoporous Nano- and Micron-Bioactive Glass Particles.Macrophage-derived MCPIP1 mediates silica-induced pulmonary fibrosis via autophagy.Role of oxidative damage in toxicity of particulates.BBC3 in macrophages promoted pulmonary fibrosis development through inducing autophagy during silicosis.Nanoparticles: molecular targets and cell signalling.The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles.Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages.Evaluation of the toxicity of food additive silica nanoparticles on gastrointestinal cells.Mechanism of cellular uptake of genotoxic silica nanoparticlesThe protective effects of hydroxytyrosol against ortho-phenylphenol-induced DNA damage in HepG2 cells.Silica and double-stranded RNA synergistically induce bronchial epithelial apoptosis and airway inflammation.Imipramine blocks acute silicosis in a mouse model.The acidic transformed nano-VO2 causes macrophage cell death by the induction of lysosomal membrane permeabilization and Ca2+ efflux.Protein kinase C-δ isoform mediates lysosome labilization in DNA damage-induced apoptosisNanomaterial cytotoxicity is composition, size, and cell type dependent.Single Cell Analysis of Phagocytosis, Phagosome Maturation, Phagolysosomal Leakage, and Cell Death Following Exposure of Macrophages to Silica Particles.N-acetylcysteine alleviated silica-induced lung fibrosis in rats by down-regulation of ROS and mitochondrial apoptosis signaling.Lysosomal membrane permeabilization causes secretion of IL-1β in human vascular smooth muscle cells
P2860
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P2860
Silica-induced apoptosis in mouse alveolar macrophages is initiated by lysosomal enzyme activity.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Silica-induced apoptosis in mo ...... by lysosomal enzyme activity.
@en
type
label
Silica-induced apoptosis in mo ...... by lysosomal enzyme activity.
@en
prefLabel
Silica-induced apoptosis in mo ...... by lysosomal enzyme activity.
@en
P2093
P2860
P356
P1476
Silica-induced apoptosis in mo ...... by lysosomal enzyme activity.
@en
P2093
Andrea K Hubbard
Charles Giardina
David A Knecht
Joseph Helble
Michael S Thibodeau
P2860
P356
10.1093/TOXSCI/KFH121
P577
2004-03-31T00:00:00Z