Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation.
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Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseExpression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breastThe Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cellsIon channels and transporters in tumour cell migration and invasionExtracellular alkaline pH leads to increased metastatic potential of estrogen receptor silenced endocrine resistant breast cancer cellsIon transporters in brain tumorsExpression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchangerPhospholipase C-beta1 mediates alpha1-adrenergic receptor-stimulated activation of the sodium-hydrogen exchanger in Chinese hamster lung fibroblasts (CCL39)Proton, diffusion-weighted imaging, and sodium (23Na) MRI of uterine leiomyomata after MR-guided high-intensity focused ultrasound: a preliminary study.The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.Concentration-independent MRI of pH with a dendrimer-based pH-responsive nanoprobeTumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.Prolonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib (Iressa(TM)) and to the antiangiogenic agent ZD6474: Cytotoxic and biomolecular effects.[Pt(O,O'-acac)(γ-acac)(DMS)] alters SH-SY5Y cell migration and invasion by the inhibition of Na+/H+ exchanger isoform 1 occurring through a PKC-ε/ERK/mTOR Pathway.MRI of the tumor microenvironment.The Na⁺/H⁺ exchanger (NHE1) as a novel co-adjuvant target in paclitaxel therapy of triple-negative breast cancer cellsSpatial profiles of markers of glycolysis, mitochondria, and proton pumps in a rat glioma suggest coordinated programming for proliferation.Cortactin phosphorylation regulates cell invasion through a pH-dependent pathwayCLCA2 as a p53-inducible senescence mediator.A developmentally regulated Na-H exchanger in Dictyostelium discoideum is necessary for cell polarity during chemotaxis.Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma.Role of the Na/H exchanger NHE1 in cell migration.Physiological role and regulation of the Na+/H+ exchanger.SLC9/NHE gene family, a plasma membrane and organellar family of Na⁺/H⁺ exchangersRegulation of cell survival by Na+/H+ exchanger-1.Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression.Na+/H+ exchanger NHE1 regulation modulates metastatic potential and epithelial-mesenchymal transition of triple-negative breast cancer cells.NHE-1: a molecular target for signalling and cell matrix interactions.The Na+/H+ exchanger NHE1 is required for directional migration stimulated via PDGFR-alpha in the primary cilium.Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.Bioelectric mechanisms in regeneration: Unique aspects and future perspectives.Cell volume homeostatic mechanisms: effectors and signalling pathways.Roles of ion transport in control of cell motility.Na+/H+ exchangers.Traditional and emerging roles for the SLC9 Na+/H+ exchangers.Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment.Role of pHi, and proton transporters in oncogene-driven neoplastic transformation.Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.Expression of ATP6V1C1 during oral carcinogenesis.
P2860
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P2860
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Phosphoinositide 3-kinase is i ...... induced by serum deprivation.
@en
type
label
Phosphoinositide 3-kinase is i ...... induced by serum deprivation.
@en
prefLabel
Phosphoinositide 3-kinase is i ...... induced by serum deprivation.
@en
P2093
P2860
P356
P1476
Phosphoinositide 3-kinase is i ...... induced by serum deprivation.
@en
P2093
A Bellizzi
A Paradiso
M Tommasino
S J Reshkin
V Albarani
V Casavola
P2860
P304
P356
10.1074/JBC.275.8.5361
P407
P577
2000-02-01T00:00:00Z