Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin.
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Promotion of G alpha i3 subunit down-regulation by GIPN, a putative E3 ubiquitin ligase that interacts with RGS-GAIPThe heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycinThe G protein α chaperone Ric-8 as a potential therapeutic targetA proteomic snapshot of the human heat shock protein 90 interactomeGeldanamycin: the prototype of a class of antitumor drugs targeting the heat shock protein 90 family of molecular chaperonesDegradation of the non-palmitoylated invertebrate visual guanine-nucleotide binding protein, iGq alpha(C3,4A), by the ubiquitin-proteasomal pathway is regulated by its activation and translocation to the cytoplasm.[EXPRESS] Peripheral inflammatory injury alters the relative abundance of Gα subunits in the dorsal horn of the spinal cord and in the rostral ventromedial medulla of male rats.Hsp90: chaperoning signal transduction.HSP90 as a new therapeutic target for cancer therapy: the story unfolds.Seven-transmembrane receptors and ubiquitinationHIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.Molecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunits.Ric-8 regulation of heterotrimeric G proteins.Proteasome involvement in the degradation of the G(q) family of Galpha subunits.Regulation of the atrial natriuretic peptide receptor by heat shock protein 90 complexes.Autoregulation of glucocorticoid receptor by cortisol in rainbow trout hepatocytes.NMR chemical shift perturbation study of the N-terminal domain of Hsp90 upon binding of ADP, AMP-PNP, geldanamycin, and radicicol.Coordinate expression of the alpha and beta subunits of heterotrimeric G proteins involves regulation of protein degradation in CHO cells.Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.Expression of the GTP-binding protein Gαs in human myometrial cells is regulated by ubiquitination and protein degradation: involvement of proteasomal inhibition by trichostatin A.
P2860
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P2860
Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin.
description
2000 nî lūn-bûn
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name
Degradation of heterotrimeric ...... pecific compound geldanamycin.
@en
type
label
Degradation of heterotrimeric ...... pecific compound geldanamycin.
@en
prefLabel
Degradation of heterotrimeric ...... pecific compound geldanamycin.
@en
P2093
P2860
P356
P1476
Degradation of heterotrimeric ...... pecific compound geldanamycin.
@en
P2093
P2860
P304
P356
10.1074/JBC.275.3.1565
P407
P577
2000-01-01T00:00:00Z