ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.

ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.

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http://www.wikidata.org/entity/Q40912652
Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationMeprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.The role of ADAM17 in the T-cell response against bacterial pathogens.A Role for Soluble IL-6 Receptor in Osteoarthritis.ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma.Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like CellsControl of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cellsADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
P2860

ADAM17 controls IL-6 signaling by cleavage of the murine IL-6Rα from the cell surface of leukocytes during inflammatory responses.

Item
http://www.wikidata.org/entity/Q40912652
description
2015 nî lūn-bûn
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2015年の論文
@ja
2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
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2015年學術文章
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2015年學術文章
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name
ADAM17 controls IL-6 signaling ...... during inflammatory responses.
@en
type
label
ADAM17 controls IL-6 signaling ...... during inflammatory responses.
@en
prefLabel
ADAM17 controls IL-6 signaling ...... during inflammatory responses.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
ADAM17 controls IL-6 signaling ...... during inflammatory responses.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698