Modulation of invasive properties of murine squamous carcinoma cells by heterologous expression of cathepsin B and cystatin C.
about
Cysteine proteinase inhibitor cystatin C in squamous cell carcinoma of the head and neck: relation to prognosisImportance of lysosomal cysteine proteases in lung diseaseSynergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.Overexpression of cystatin SN positively affects survival of patients with surgically resected esophageal squamous cell carcinoma.Expression of Cystatin SN significantly correlates with recurrence, metastasis, and survival duration in surgically resected non-small cell lung cancer patients.Expression of cystatin C and its effect on EC9706 cells in esophageal carcinoma.Cathepsins mediate tumor metastasis.Cystatin SN neutralizes the inhibitory effect of cystatin C on cathepsin B activity.Proteinases and their inhibitors in liver cancer.V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activation in vivo.Cystatin C properties crucial for uptake and inhibition of intracellular target enzymes.The mannose 6-phosphate-binding sites of M6P/IGF2R determine its capacity to suppress matrix invasion by squamous cell carcinoma cells.M6P/IGF2R modulates the invasiveness of liver cells via its capacity to bind mannose 6-phosphate residuesMatrigel invasion by the prostate cancer cell lines, PC3 and DU145, and cathepsin L+B activity.Decreased activity of cathepsins L + B and decreased invasive ability of PC3 prostate cancer cells.Invasion of ras-transformed breast epithelial cells depends on the proteolytic activity of cysteine and aspartic proteinases.CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells.The mannose 6-phosphate/insulin-like growth factor II receptor restricts the tumourigenicity and invasiveness of squamous cell carcinoma cells.Cerebrospinal fluid cathepsin B and S.Down-regulation of cathepsin B expression impairs the invasive and tumorigenic potential of human glioblastoma cells.Low-level internalization of cystatin E/M affects legumain activity and migration of melanoma cells.Elevated serum cathepsin B concentration in pregnant women is associated with preeclampsia.
P2860
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P2860
Modulation of invasive properties of murine squamous carcinoma cells by heterologous expression of cathepsin B and cystatin C.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Modulation of invasive propert ...... of cathepsin B and cystatin C.
@en
type
label
Modulation of invasive propert ...... of cathepsin B and cystatin C.
@en
prefLabel
Modulation of invasive propert ...... of cathepsin B and cystatin C.
@en
P2093
P1476
Modulation of invasive propert ...... of cathepsin B and cystatin C.
@en
P2093
H Schwihla
M Abrahamson
N Katunuma
O Schlappack
S Coulibaly
P2860
P304
P356
10.1002/(SICI)1097-0215(19991112)83:4<526::AID-IJC15>3.0.CO;2-M
P577
1999-11-01T00:00:00Z