CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
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Thymoquinone attenuates tumor growth in ApcMin mice by interference with Wnt-signalingDifferential gene expression profile reveals deregulation of pregnancy specific beta1 glycoprotein 9 early during colorectal carcinogenesis.Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidneyThe cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathwayWnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells.Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecityExpression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model systemThe homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesisLoss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colonBeta-catenin--a linchpin in colorectal carcinogenesis?Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulationp21 in cancer: intricate networks and multiple activitiesFunctional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma.Linking the ovarian cancer transcriptome and immunomePositive feedback regulation between phospholipase D and Wnt signaling promotes Wnt-driven anchorage-independent growth of colorectal cancer cells.Targeted inactivation of CTNNB1 reveals unexpected effects of beta-catenin mutationPinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis.Transcriptional regulation of the intestinal nuclear bile acid farnesoid X receptor (FXR) by the caudal-related homeobox 2 (CDX2).Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.Initiation of trophectoderm lineage specification in mouse embryos is independent of Cdx2.A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 statusWnt/β-catenin signaling regulates Yes-associated protein (YAP) gene expression in colorectal carcinoma cellsComputational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines.Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathwaySOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genesSnf1-related kinase inhibits colon cancer cell proliferation through calcyclin-binding protein-dependent reduction of β-catenin.CDX2 is an amplified lineage-survival oncogene in colorectal cancer.Decreased expression of the gut-enriched Krüppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients.CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling.The Role of Chromosomal Instability and Epigenetics in Colorectal Cancers Lacking β-Catenin/TCF Regulated TranscriptionKLF4 regulation in intestinal epithelial cell maturationMicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesisPou homeodomain protein OCT1 is implicated in the expression of the caudal-related homeobox gene Cdx-2.Morphological and transcriptional responses of untransformed intestinal epithelial cells to an oncogenic beta-catenin protein.A novel bidirectional positive-feedback loop between Wnt-β-catenin and EGFR-ERK plays a role in context-specific modulation of epithelial tissue regeneration.Differential roles of EPS8 in carcinogenesis: loss of protein expression in a subset of colorectal carcinoma and adenoma.Distinct roles for Wnt-4 and Wnt-11 during retinoic acid-induced neuronal differentiation.CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype.
P2860
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P2860
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
@en
type
label
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
@en
prefLabel
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
@en
P2093
P356
P1433
P1476
CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling.
@en
P2093
A B Sparks
L T da Costa
P2888
P304
P356
10.1038/SJ.ONC.1202872
P407
P577
1999-09-01T00:00:00Z
P5875
P6179
1006228955